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sample_name:"23S Ribosomal RNA" AND release_date:[2023-01-01T00:00:00Z TO 2023-12-31T23:59:59Z]
Bacillus subtilis MutS2-collided disome complex (stalled 70S)
Release date: Dec. 27, 2023
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8qpp
Q-score: 0.415
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8qpp
Q-score: 0.415
Park EN, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR
EMBO J (2024) 43 pp. 484-506 [ Pubmed: 38177497 DOI: doi:10.1038/s44318-023-00010-3 ]
Sample:
- Large ribosomal subunit protein bl34 (5 kDa, Protein from Bacillus subtilis)
- 50s ribosomal protein l19 (13 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein bl20 (13 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein ul30 (6 kDa, Protein from Bacillus subtilis)
- 50s ribosomal protein l15 (15 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein bl27 (8 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein ul3 (22 kDa, Protein from Bacillus subtilis)
- Mrna (33-mer) (10 kDa, RNA from Bacillus subtilis)
- 50s ribosomal protein l36 (4 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s11 (13 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s20 (9 kDa, Protein from Bacillus subtilis)
- Endonuclease muts2 (87 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s9 (14 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s17 (10 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s3 (24 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein ul16 (15 kDa, Protein from Bacillus subtilis)
- 50s ribosomal protein l9 (16 kDa, Protein from Bacillus subtilis)
- 50s ribosomal protein l14 (13 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein bl21 (11 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s14 type z (7 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s18 (8 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s16 (10 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein ul29 (7 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s4 (22 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein ul13 (16 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein bl17 (13 kDa, Protein from Bacillus subtilis)
- 5s rrna (112-mer) (36 kDa, RNA from Bacillus subtilis)
- Large ribosomal subunit protein ul23 (10 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s5 (17 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s7 (17 kDa, Protein from Bacillus subtilis)
- 16s rrna (1533-mer) (496 kDa, RNA from Bacillus subtilis)
- 30s ribosomal protein s19 (10 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s13 (13 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein bl35 (7 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s15 (10 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein ul5 (20 kDa, Protein from Bacillus subtilis)
- Trna (77-mer) (24 kDa, RNA from Bacillus subtilis)
- 30s ribosomal protein s12 (15 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s6 (11 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s10 (11 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein bl28 (6 kDa, Protein from Bacillus subtilis)
- 30s ribosomal protein s2 (28 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein bl31 (7 kDa, Protein from Bacillus subtilis)
- 50s ribosomal protein l18 (12 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein ul22 (12 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein ul4 (22 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein ul24 (10 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein bl33 (5 kDa, Protein from Bacillus subtilis)
- 50s ribosomal protein l32 (6 kDa, Protein from Bacillus subtilis)
- 23s ribosomal rna (949 kDa, RNA from Bacillus subtilis)
- Large ribosomal subunit protein ul6 (19 kDa, Protein from Bacillus subtilis)
- Large ribosomal subunit protein ul2 (30 kDa, Protein from Bacillus subtilis)
- Muts2-disome complex from b. subtilis, focus refined, stalled 70s (Complex from Bacillus subtilis)
- 30s ribosomal protein s8 (14 kDa, Protein from Bacillus subtilis)
The structure of a hibernating ribosome in the Lyme disease pathogen
Release date: Nov. 8, 2023
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8fmw
Q-score: 0.484
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8fmw
Q-score: 0.484
Sharma MR, Manjari SR, Agrawal EK, Keshavan P, Koripella RK, Majumdar S, Marcinkiewicz AL, Lin YP, Agrawal RK, Banavali NK
Nat Commun (2023) 14 pp. 6961-6961 [ Pubmed: 37907464 DOI: doi:10.1038/s41467-023-42266-7 ]
Sample:
- 50s ribosomal protein l33 (6 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l35 (7 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l31 type b (9 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l14 (13 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l22 (13 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l23 (11 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s20 (9 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s7 (18 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s6 (11 kDa, Protein from Borreliella burgdorferi B31)
- E-site t-rna (24 kDa, RNA from Borreliella burgdorferi B31)
- 50s ribosomal protein l27 (8 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s4 (24 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l13 (16 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s8 (14 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l4 (23 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s17 (9 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l9 (17 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l19 (13 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s10 (11 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein bl38 (5 kDa, Protein from Borreliella burgdorferi B31)
- 16s ribosomal rna (495 kDa, RNA from Borreliella burgdorferi B31)
- Ribosomal subunit interface protein (11 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l18 (13 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l25 (20 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s14 type z (7 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l32 (6 kDa, Protein from Borreliella burgdorferi B31)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l3 (22 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s21 (8 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s5 (17 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s15 (10 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l5 (20 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l24 (11 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l29 (7 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s9 (14 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s12 (13 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein ul30 (11 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s18 (7 kDa, Protein from Borreliella burgdorferi B31)
- Hibernating 70s ribosome bound to e-trna and hibernation promoting factor protein (2 MDa, Complex from Borreliella burgdorferi)
- 50s ribosomal protein l21 (12 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l15 (16 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l36 (4 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s11 (12 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l28 (10 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l34 (6 kDa, Protein from Borreliella burgdorferi B31)
- 5s ribosomal rna (36 kDa, RNA from Borreliella burgdorferi B31)
- 50s ribosomal protein l17 (14 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s19 (9 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l10 (18 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l16 (15 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s13 (12 kDa, Protein from Borreliella burgdorferi B31)
- 23s ribosomal rna (948 kDa, RNA from Borreliella burgdorferi B31)
- 30s ribosomal protein s3 (23 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein s16 (9 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l11 (14 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l20 (13 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l6 (19 kDa, Protein from Borreliella burgdorferi B31)
- 30s ribosomal protein bs22 (3 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l1 (25 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l2 (30 kDa, Protein from Borreliella burgdorferi B31)
The structure of a 50S ribosomal subunit in the Lyme disease pathogen Borreliella burgdorferi
Release date: Nov. 8, 2023
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8fn2
Q-score: 0.379
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8fn2
Q-score: 0.379
Sharma MR, Manjari SR, Agrawal EK, Keshavan P, Koripella RK, Majumdar S, Marcinkiewicz AL, Lin YP, Agrawal RK, Banavali NK
Nat Commun (2023) 14 pp. 6961-6961 [ Pubmed: 37907464 DOI: doi:10.1038/s41467-023-42266-7 ]
Sample:
- 50s ribosomal protein l33 (6 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l35 (7 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l31 type b (9 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l14 (13 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l22 (13 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l23 (11 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l27 (8 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l13 (16 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l4 (23 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l9 (17 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l19 (13 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein bl38 (5 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l18 (13 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l25 (20 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l32 (6 kDa, Protein from Borreliella burgdorferi B31)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l3 (22 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l5 (20 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal subunit (Complex from Borreliella burgdorferi)
- 50s ribosomal protein l24 (11 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l29 (7 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein ul30 (11 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l21 (12 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l15 (16 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l36 (4 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l28 (10 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l34 (6 kDa, Protein from Borreliella burgdorferi B31)
- 5s ribosomal rna (36 kDa, RNA from Borreliella burgdorferi B31)
- 50s ribosomal protein l17 (14 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l16 (15 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l10 (18 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l20 (13 kDa, Protein from Borreliella burgdorferi B31)
- 23s ribosomal rna (948 kDa, RNA from Borreliella burgdorferi B31)
- 50s ribosomal protein l11 (14 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l6 (19 kDa, Protein from Borreliella burgdorferi B31)
- 50s ribosomal protein l2 (30 kDa, Protein from Borreliella burgdorferi B31)
Release date: Aug. 9, 2023
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8syl
Q-score: 0.544
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8syl
Q-score: 0.544
Seely SM, Parajuli NP, De Tarafder A, Ge X, Sanyal S, Gagnon MG
Nat Commun (2023) 14 pp. 4666-4666 [ DOI: doi:10.1038/s41467-023-40416-5 Pubmed: 37537169 ]
Sample:
- 30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- Phenylalanine trna (24 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli)
- (2s)-n-[(1r,2s,3s,4r,5s)-4-[(2r,3r,4s,5s,6r)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2s,3r,4s,5s ,6r)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide (585 Da, Ligand)
- 30s ribosomal protein s11 (13 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s5 (17 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s21 (8 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l15 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s2 (26 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s19 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli)
- Ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- Escherichia coli 70s ribosome in complex with amikacin, mrna, and a-, p-, and e-site trnas (2 MDa, Complex from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli)
- Phenylalanine (165 Da, Ligand)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- 30s ribosomal protein s18 (9 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s6 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 16s ribosomal rna (499 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli)
- Water (18 Da, Ligand)
- 30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- M-f-stop mrna (7 kDa, RNA from Escherichia phage T4)
- 50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s13 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s7 (17 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s3 (26 kDa, Protein from Escherichia coli)
- P-site initiator trna (24 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli)
E. coli 50S ribosome bound to compound streptogramin A analog 3142
Release date: June 28, 2023
Resolution: 1.91 Å
EM Method: Single-particle
Fitted PDBs: 8e30
Q-score: 0.629
Resolution: 1.91 Å
EM Method: Single-particle
Fitted PDBs: 8e30
Q-score: 0.629
Li Q, Pellegrino J, Lee DJ, Fraser JS, Seiple IB
To Be Published
Sample:
- 50s e. coli ribosome (Complex from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- N-{2-[4-(aminomethyl)-1h-1,2,3-triazol-1-yl]ethyl}-2-[(3r,4r,5e,10e,12e,14s,16r,23s,26ar)-16-fluoro-14-hydroxy-12-methyl-1,7,22-trioxo-3-(propan-2-yl)-4,7,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1h,3h,22h-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosin-4-yl]acetamide (698 Da, Ligand)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
E. coli 50S ribosome bound to compound streptogramin analogs SA1 and SB1
Release date: June 28, 2023
Resolution: 2.35 Å
EM Method: Single-particle
Fitted PDBs: 8e32
Q-score: 0.609
Resolution: 2.35 Å
EM Method: Single-particle
Fitted PDBs: 8e32
Q-score: 0.609
Takahashi Y, Pellegrino J, Lee DJ, Fraser JS, Seiple IB
To Be Published
Sample:
- 50s e. coli ribosome (Complex from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- Water (18 Da, Ligand)
- (3r,4r,5e,10e,12e,14s,16r,23s,26ar)-16-fluoro-14-hydroxy-12-methyl-3-(propan-2-yl)-4-(prop-2-yn-1-yl)-3,4,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1h,7h,22h-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,22-trione (555 Da, Ligand)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- ~{n}-[(3~{s},6~{s},12~{r},15~{s},16~{r},19~{s},22~{s},24~{r})-12-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethyl]-4,16-dimethyl-24-oxidanyl-2,5,11,14,18,21-hexakis(oxidanylidene)-19-phenyl-3-(phenylmethyl)-17-oxa-1,4,10,13,20-pentazatricyclo[20.4.0.0^{6,10}]hexacosan-15-yl]-3-oxidanyl-pyridine-2-carboxamide (867 Da, Ligand)
E. coli 50S ribosome bound to compound streptogramin analog SAB001
Release date: June 28, 2023
Resolution: 2.23 Å
EM Method: Single-particle
Fitted PDBs: 8e33
Q-score: 0.602
Resolution: 2.23 Å
EM Method: Single-particle
Fitted PDBs: 8e33
Q-score: 0.602
Takahashi Y, Pellegrino J, Lee DJ, Fraser JS, Seiple IB
To Be Published
Sample:
- 50s e. coli ribosome (Complex from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- N-{(4r,6r,9s,10r,13s,15as,17r,20r,22s,24as)-22-benzyl-6-[2-(4-{[(3r,4r,5e,10e,12e,14s,16r,23s,26ar)-16-fluoro-14-hydroxy-12-methyl-1,7,22-trioxo-3-(propan-2-yl)-4,7,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1h,3h,22h-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosin-4-yl]methyl}-1h-1,2,3-triazol-1-yl)ethyl]-17-hydroxy-10,23-dimethyl-5,8,12,15,21,24-hexaoxo-13-phenyldocosahydro-12h-pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecin-9-yl}-3-hydroxypyridine-2-carboxamide (1 kDa, Ligand)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- Water (18 Da, Ligand)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
E. coli 50S ribosome bound to compound SAB002
Release date: June 28, 2023
Resolution: 2.27 Å
EM Method: Single-particle
Fitted PDBs: 8e35
Q-score: 0.569
Resolution: 2.27 Å
EM Method: Single-particle
Fitted PDBs: 8e35
Q-score: 0.569
Takahashi Y, Pellegrino J, Lee DJ, Fraser JS, Seiple IB
To Be Published
Sample:
- 50s e. coli ribosome (Complex from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- Water (18 Da, Ligand)
- N-{(4r,6r,9s,10r,13s,15as,17r,20r,22s,24as)-22-benzyl-6-[3-(4-{[(3r,4r,5e,10e,12e,14s,16r,23r,26ar)-16-fluoro-14-hydroxy-12-methyl-1,7,22-trioxo-3-(propan-2-yl)-4,7,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1h,3h,22h-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosin-4-yl]methyl}-1h-1,2,3-triazol-1-yl)propyl]-17-hydroxy-10,23-dimethyl-5,8,12,15,21,24-hexaoxo-13-phenyldocosahydro-12h-pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecin-9-yl}-3-hydroxypyridine-2-carboxamide (1 kDa, Ligand)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
E. coli 50S ribosome bound to compound streptogramin A analog 3146
Release date: June 28, 2023
Resolution: 2.38 Å
EM Method: Single-particle
Fitted PDBs: 8e36
Q-score: 0.57
Resolution: 2.38 Å
EM Method: Single-particle
Fitted PDBs: 8e36
Q-score: 0.57
Li Q, Pellegrino J, Lee DJ, Seiple IB, Fraser JS
To Be Published
Sample:
- 50s e. coli ribosome (Complex from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 2-[(3r,4r,5e,10e,12e,14s,16r,23s,26ar)-16-fluoro-14-hydroxy-12-methyl-1,7,22-trioxo-3-(propan-2-yl)-4,7,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1h,3h,22h-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosin-4-yl]-n-{2-[4-(pyridin-4-yl)-1h-1,2,3-triazol-1-yl]ethyl}acetamide (746 Da, Ligand)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
E. coli 50S ribosome bound to solithromycin and VM1
Release date: June 28, 2023
Resolution: 1.99 Å
EM Method: Single-particle
Fitted PDBs: 8e3o
Q-score: 0.618
Resolution: 1.99 Å
EM Method: Single-particle
Fitted PDBs: 8e3o
Q-score: 0.618
Boyce JH, Pellegrino J, Lee DJ, Ecker AK, Seiple IB, Fraser JS
To Be Published
Sample:
- 50s e. coli ribosome (Complex from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- Virginiamycin m1 (525 Da, Ligand)
- (3as,4r,7s,9r,10r,11r,13r,15r,15ar)-1-{4-[4-(3-aminophenyl)-1h-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2h-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-d-xylo-hexopyranoside (845 Da, Ligand)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)