Full length human cytoplasmic dynein-1 in the phi-particle conformation
Resolution: 15.0 Å
EM Method: Single-particle
Fitted PDBs: 5nvu
Q-score: 0.087
Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP
Cell (2017) 169 pp. 1303-1314.e18 [ DOI: doi:10.1016/j.cell.2017.05.025 Pubmed: 28602352 ]
- Dynein tail heavy chain (76 kDa, Protein from Homo sapiens)
- Lc8 (7 kDa, Protein from Homo sapiens)
- Robl (10 kDa, Protein from Homo sapiens)
- N-terminal dimerization domain (10 kDa, Protein from Homo sapiens)
- Tctex (8 kDa, Protein from Homo sapiens)
- Complete human cytoplasmic dynein-1 in the phi-particle conformation (Complex from Homo sapiens)
- N-terminal dimerization domain (10 kDa, Protein from Homo sapiens)
- Intermediate chain n-terminus peptides (2 kDa, Protein from Homo sapiens)
- Dynein intermediate chain (29 kDa, Protein from Homo sapiens)
- Dynein light intermediate chain (25 kDa, Protein from Homo sapiens)
- Dynein light intermediate chain (25 kDa, Protein from Homo sapiens)
- Dynein motor domain (269 kDa, Protein from Homo sapiens)
- Tctex (8 kDa, Protein from Homo sapiens)
- Dynein tail heavy chain (79 kDa, Protein from Homo sapiens)
- Intermediate chain n-terminus peptides (2 kDa, Protein from Homo sapiens)
Human cytoplasmic dynein-1 bound to dynactin and an N-terminal construct of BICD2
Resolution: 8.7 Å
EM Method: Single-particle
Fitted PDBs: 5nw4
Q-score: 0.113
Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP
Cell (2017) 169 pp. 1303-1314.e18 [ DOI: doi:10.1016/j.cell.2017.05.025 Pubmed: 28602352 ]
- Dynactin (5 kDa, Protein from Pig)
- Dynein-1 (Complex from Homo sapiens)
- F-actin capping protein beta subunit variant ii (33 kDa, Protein from Pig)
- Dynein heavy chain (78 kDa, Protein from Homo sapiens)
- Dynein intermediate chain (29 kDa, Protein from Homo sapiens)
- Dynein light intermediate chain (25 kDa, Protein from Homo sapiens)
- Dynactin 6 (20 kDa, Protein from Pig)
- Arp1 (42 kDa, Protein from Pig)
- Dynactin (7 kDa, Protein from Pig)
- Dynactin (Complex from Sus scrofa)
- Dynactin shoulder complex (14 kDa, Protein from Pig)
- Dynein n-terminal dimerization domain (10 kDa, Protein from Homo sapiens)
- Beta-actin (43 kDa, Protein from Pig)
- Capping protein (actin filament) muscle z-line, alpha 1 (33 kDa, Protein from Pig)
- Dynactin (3 kDa, Protein from Pig)
- Robl (10 kDa, Protein from Homo sapiens)
- Bicd2 (Complex from Homo sapiens)
- Dynactin pointed end p62 (20 kDa, Protein from Pig)
- Dynein intermediate chain (29 kDa, Protein from Homo sapiens)
- Bicd2n (23 kDa, Protein from Homo sapiens)
- P150 (4 kDa, Protein from Pig)
- Dynein light intermediate chain (25 kDa, Protein from Homo sapiens)
- Dynactin shoulder complex (51 kDa, Protein from Pig)
- Dynactin p150 (4 kDa, Protein from Pig)
- Dynactin shoulder complex (48 kDa, Protein from Pig)
- Dynactin subunit 5 (24 kDa, Protein from Pig)
- Arp11 (46 kDa, Protein from Pig)
- Human cytoplasmic dynein-1 bound to dynactin and an n-terminal construct of bicd2 (2 MDa, Complex)
- Dynein n-terminal dimerization domain (10 kDa, Protein from Homo sapiens)
- Dynactin (2 kDa, Protein from Pig)
- Dynactin shoulder complex (11 kDa, Protein from Pig)
- Dynein heavy chain (75 kDa, Protein from Homo sapiens)
motor domain of complete human dynein-1 in the state of phi-particle
Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP
Cell (2017) 169 pp. 1303-1314.e18 [ DOI: doi:10.1016/j.cell.2017.05.025 Pubmed: 28602352 ]
- Motor domains from human cytoplasmic dynein-1 in the phi-particle conformation (Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Cytoplasmic dynein 1 heavy chain 1 (533 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Human cytoplasmic dynein-1 tail in the twisted state
Resolution: 8.4 Å
EM Method: Single-particle
Fitted PDBs: 5nvs
Q-score: 0.028
Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP
Cell (2017) 169 pp. 1303-1314.e18 [ DOI: doi:10.1016/j.cell.2017.05.025 Pubmed: 28602352 ]
- N-terminal dimerization domain (10 kDa, Protein from Homo sapiens)
- N-terminal dimerization domain (10 kDa, Protein from Homo sapiens)
- Dynein intermediate chain (29 kDa, Protein from Homo sapiens)
- Dynein light intermediate chain (25 kDa, Protein from Homo sapiens)
- Robl (10 kDa, Protein from Homo sapiens)
- Human cytoplasmic dynein-1 tail in the twisted n-terminus state (1 MDa, Complex from Homo sapiens)
- Dynein light intermediate chain (25 kDa, Protein from Homo sapiens)
- Tctex (8 kDa, Protein from Homo sapiens)
- Lc8 (7 kDa, Protein from Homo sapiens)
- Tctex (8 kDa, Protein from Homo sapiens)
- Dynein heavy chain (79 kDa, Protein from Homo sapiens)
- Intermediate chain (2 kDa, Protein from Homo sapiens)
- Dynein heavy chain (76 kDa, Protein from Homo sapiens)
- Intermediate chain (2 kDa, Protein from Homo sapiens)
Human cytoplasmic dynein-1 tail in the parallel state
Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP
Cell (2017) 169 pp. 1303-1314.e18 [ DOI: doi:10.1016/j.cell.2017.05.025 Pubmed: 28602352 ]
Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP
Cell (2017) 169 pp. 1303-1314.e18 [ DOI: doi:10.1016/j.cell.2017.05.025 Pubmed: 28602352 ]