Do data resources managed by EMBL-EBI and our collaborators make a difference to your work? Please take 10 minutes to fill in our annual user survey, and help us make the case for why sustaining open data resources is critical for life sciences research. We appreciate your responses prior to closing of the survey on Monday 17th June.
Cryo-EM structure of bsAb3 Fab-Gn-Gc complex
Chang Z, Gao D, Liao L, Sun J, Zhang G, Zhang X, Wang F, Li C, Oladejo BO, Li S, Chai Y, Hu Y, Lu X, Xiao H, Qi J, Chen Z, Gao F, Wu Y
PNAS (2024) 121 pp. e2400163121-e2400163121 [ Pubmed: 38830098 DOI: doi:10.1073/pnas.2400163121 ]
- Bsab3 fab-heavy chain (37 kDa, Protein from Homo sapiens)
- Glycoprotein c (47 kDa, Protein from Dabie bandavirus)
- The structure of bsab3_gn_gc complex (Complex)
- Glycoprotein n (35 kDa, Protein from Dabie bandavirus)
- Gn_gc (Complex from Dabie bandavirus)
- Bsab3 fab-light chain (35 kDa, Protein from Homo sapiens)
- Fab (Complex from Homo sapiens)
Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 8j86
Q-score: 0.362
Xu Y, Wu Y, Wu X, Zhang Y, Yang Y, Li D, Yang B, Gao K, Zhang Z, Dong C
Int J Biol Macromol (2024) 270 pp. 132231-132231 [ DOI: doi:10.1016/j.ijbiomac.2024.132231 Pubmed: 38735603 ]
- Dna polymerase processivity factor component a20 (49 kDa, Protein from Monkeypox virus)
- Calcium ion (40 Da, Ligand)
- Monkeypox virus replication holoenzyme f8-a22-e4 complex with dna duplex only (191 MDa, Complex from Monkeypox virus)
- Dna (5'-d(p*ap*gp*cp*tp*gp*cp*tp*ap*tp*gp*tp*gp*ap*gp*ap*tp*tp*ap*ap*gp*tp*tp*ap*t)-3') (7 kDa, DNA from DNA molecule)
- Dna polymerase (120 kDa, Protein from Monkeypox virus)
- Dna (5'-d(p*gp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*gp*ap*tp*ap*ap*cp*tp*tp*ap*ap*tp*cp*tp*cp*ap*cp*ap*tp*ap*gp*cp*ap*gp*cp*tp*)-3') (11 kDa, DNA from DNA molecule)
- E4r (27 kDa, Protein from Monkeypox virus)
Type IV pilus from Pseudomonas PAO1 strain
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8tum
Q-score: 0.448
Thongchol J, Yu Z, Harb L, Lin Y, Koch M, Theodore M, Narsaria U, Shaevitz J, Gitai Z, Wu Y, Zhang J, Zeng L
Science (2024) 384 pp. eadl0635-eadl0635 [ DOI: doi:10.1126/science.adl0635 Pubmed: 38574145 ]
- Type iv major pilin protein pila (14 kDa, Protein from Pseudomonas aeruginosa PAO1)
- Type iv twitching pilus (240 kDa, Cellular component from Pseudomonas aeruginosa)
Asymmetric reconstruction of mature PP7 virions
Thongchol J, Yu Z, Harb L, Lin Y, Koch M, Theodore M, Narsaria U, Shaevitz J, Gitai Z, Wu Y, Zhang J, Zeng L
Science (2024) 384 pp. eadl0635-eadl0635 [ DOI: doi:10.1126/science.adl0635 Pubmed: 38574145 ]
- Type iv twitching pilus (240 kDa, Cellular component from Pseudomonas aeruginosa)
Composite map of PP7 binding to type IV pilus from PAO1
Thongchol J, Yu Z, Harb L, Lin Y, Koch M, Theodore M, Narsaria U, Shaevitz J, Gitai Z, Wu Y, Zhang J, Zeng L
Science (2024) 384 pp. eadl0635-eadl0635 [ DOI: doi:10.1126/science.adl0635 Pubmed: 38574145 ]
- Type iv twitching pilus (240 kDa, Cellular component from Pseudomonas aeruginosa)
Gi bound CCR8 complex with nonpeptide agonist ZK 756326
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8kfy
Q-score: 0.466
Jiang S, Lin X, Wu L, Wang L, Wu Y, Xu Z, Xu F
Sci Adv (2024) 10 pp. eadj7500-eadj7500 [ Pubmed: 38306437 DOI: doi:10.1126/sciadv.adj7500 ]
- 2-[2-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]ethoxy]ethanol (356 Da, Ligand)
- C-c chemokine receptor type 8,fusion protein (65 kDa, Protein from synthetic construct)
- Scfv16 (31 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Hetero complex (Complex from Homo sapiens)
Gi bound CCR8 in ligand free state
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8kfz
Q-score: 0.351
Jiang S, Lin X, Wu L, Wang L, Wu Y, Xu Z, Xu F
Sci Adv (2024) 10 pp. eadj7500-eadj7500 [ Pubmed: 38306437 DOI: doi:10.1126/sciadv.adj7500 ]
- Scfv16 (31 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Hetero complex (Complex from Homo sapiens)
- C-c chemokine receptor type 8,lgbit fusion protein,recombinant human rhinovirus (65 kDa, Protein from synthetic construct)
Omicron spike variant BA.1 with Bn03
Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 8i4h
Q-score: 0.201
Hao A, Song W, Li C, Zhang X, Tu C, Wang X, Wang P, Wu Y, Ying T, Sun L
Signal Transduct Target Ther (2023) 8 pp. 269-269 [ DOI: doi:10.1038/s41392-023-01534-0 Pubmed: 37422451 ]
- Ba.1 (Complex from Homo sapiens)
- Bn03 (27 kDa, Protein from Homo sapiens)
- Omicron ba.1 spike with bn03 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Bn03 (Complex)
Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution: 3.93 Å
EM Method: Single-particle
Fitted PDBs: 8hl1
Q-score: 0.332
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH, Hou H, Yang B, Zhu Y, Zhang X, Zhou J
Nucleic Acids Res (2023) 51 pp. 8909-8924 [ DOI: doi:10.1093/nar/gkad661 Pubmed: 37604686 ]
- 30s ribosomal protein s27e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s17 (12 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l37e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l47a (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18 (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s2 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 23s rrna (3000-mer) (980 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l44e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s10 (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s6e (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l40e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s4e (27 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l34e (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Small ribosomal subunit protein us8 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s15 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Phe-phe-phe-phe-phe-phe (901 Da, Protein from Sulfolobus acidocaldarius DSM 639)
- Elongation factor 2 (81 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l15 (16 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s13 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l14 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s24e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s19e (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s19 (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Conserved protein (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s9 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s12 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l10e (18 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l37ae (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18ae (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s3 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l30 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s4 (19 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l15e (20 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l24e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l5 (19 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l22 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Duf2280 domain-containing protein (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s7 (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Unknown (103 Da, Ligand)
- 50s ribosomal protein l23 (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- 50s ribosomal protein l19e (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l7ae (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s11 (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s8e (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s3ae (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Mrna (5'-r(p*up*up*up*up*up*up*up*up*up*up*up*up*u)-3') (3 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s27ae (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Trna (76-mer) (24 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l6 (20 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 16s rrna (1493-mer) (484 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l29 (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l31e (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 5s rrna (122-mer) (39 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s5 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l14e (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l2 (24 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l32e (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l39e (5 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l24 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l3 (38 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l21e (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l1 (24 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l13 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s17e (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l4 (27 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s28e (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Sulfolobus acidocaldarius ribosome small sbunit (Complex from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18e (12 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s14 type z (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l30e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
Gq bound FZD1 in ligand-free state
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8j9n
Q-score: 0.386
Zhang Z, Lin X, Wei L, Wu Y, Xu L, Wu L, Wei X, Zhao S, Zhu X, Xu F
Cell Discov (2024) 10 pp. 3-3 [ Pubmed: 38182578 DOI: doi:10.1038/s41421-023-00627-y ]
- Frizzled-1 (64 kDa, Protein from Homo sapiens)
- Fzd1-gq complex in the ligand-free state (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Nanobody nb35 (16 kDa, Protein from Vicugna pacos)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short,guanine nucleotide-binding protein g(q) subunit alpha (28 kDa, Protein from Homo sapiens)