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structure of a membrane-bound glycosyltransferase
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7xe4
Q-score: 0.471
Hu X, Yang P, Chai C, Liu J, Sun H, Wu Y, Zhang M, Zhang M, Liu X, Yu H
Nature (2023) 616 pp. 190-198 [ Pubmed: 36949198 DOI: doi:10.1038/s41586-023-05856-5 ]
- Nonane (128 Da, Ligand)
- Heptane (100 Da, Ligand)
- 1,3-beta-glucan synthase component fks1 (215 kDa, Protein from baker's yeast)
- Membrane-bound glycosyltransferase (215 kDa, Complex from Saccharomyces cerevisiae)
- Tetradecane (198 Da, Ligand)
- (11r,14s)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate (495 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Decane (142 Da, Ligand)
Structure of a mutated membrane-bound glycosyltransferase
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7yuy
Q-score: 0.494
Hu X, Yang P, Chai C, Liu J, Sun H, Wu Y, Zhang M, Zhang M, Liu X, Yu H
Nature (2023) 616 pp. 190-198 [ Pubmed: 36949198 DOI: doi:10.1038/s41586-023-05856-5 ]
- Nonane (128 Da, Ligand)
- Heptane (100 Da, Ligand)
- 1,3-beta-glucan synthase component fks1 (215 kDa, Protein from Saccharomyces cerevisiae)
- Membrane-bound glycosyltransferase (215 kDa, Complex from Saccharomyces cerevisiae)
- Tetradecane (198 Da, Ligand)
- (11r,14s)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate (495 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Decane (142 Da, Ligand)
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 7wp8
Q-score: 0.441
Wu Y, Wang S, Zhang Y, Yuan L, Zheng Q, Wei M, Shi Y, Wang Z, Ma J, Wang K, Nie M, Xiao J, Huang Z, Chen P, Guo H, Lan M, Xu J, Hou W, Hong Y, Chen D, Sun H, Xiong H, Zhou M, Liu C, Guo W, Guo H, Gao J, Gan C, Li Z, Zhang H, Wang X, Li S, Cheng T, Zhao Q, Chen Y, Wu T, Zhang T, Zhang J, Cao H, Zhu H, Yuan Q, Guan Y, Xia N
Cell Host Microbe (2022) 30 pp. 1732-1744.e7 [ Pubmed: 36323313 DOI: doi:10.1016/j.chom.2022.10.011 ]
- Cryo-em structure of sars-cov-2 recombinant spike protein stfk1628x in complex with three neutralizing antibodies (Complex from Mus musculus)
- 83h7 heavy chain (13 kDa, Protein from Mus musculus)
- Spike glycoprotein (20 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 83h7 light chain (11 kDa, Protein from Mus musculus)
- Neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- 85f7 heavy chain (13 kDa, Protein from Mus musculus)
- Spike protein stfk1628x (Complex)
- 2b4 heavy chain (13 kDa, Protein from Mus musculus)
- 2b4 light chain (12 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 85f7 light chain (11 kDa, Protein from Mus musculus)
Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 7wp6
Q-score: 0.438
Wu Y, Wang S, Zhang Y, Yuan L, Zheng Q, Wei M, Shi Y, Wang Z, Ma J, Wang K, Nie M, Xiao J, Huang Z, Chen P, Guo H, Lan M, Xu J, Hou W, Hong Y, Chen D, Sun H, Xiong H, Zhou M, Liu C, Guo W, Guo H, Gao J, Gan C, Li Z, Zhang H, Wang X, Li S, Cheng T, Zhao Q, Chen Y, Wu T, Zhang T, Zhang J, Cao H, Zhu H, Yuan Q, Guan Y, Xia N
Cell Host Microbe (2022) 30 pp. 1732-1744.e7 [ Pubmed: 36323313 DOI: doi:10.1016/j.chom.2022.10.011 ]
- 36h6 heavy chain (13 kDa, Protein from Mus musculus)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 83h7 heavy chain (13 kDa, Protein from Mus musculus)
- 83h7 light chain (11 kDa, Protein from Mus musculus)
- Neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- 85f7 heavy chain (13 kDa, Protein from Mus musculus)
- 36h6 light chain (12 kDa, Protein from Mus musculus)
- Cryo-em structure of sars-cov-2 recombinant spike protein stfk in complex with three neutralizing antibodies (Complex from Mus musculus)
- Spike protein stfk (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 85f7 light chain (11 kDa, Protein from Mus musculus)
Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb nAb 2E6 (CVB1-E:2E6)
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 7x2g
Q-score: 0.515
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- 2e6 light chain (11 kDa, Protein from Mus musculus)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- Cryo-em structure of coxsackievirus b1 empty particle in complex with nab 2e6 (cvb1-e:2e6) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 pre-A particle in complex with nAb 2E6 (CVB1-pre-A:2E6)
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 7x2i
Q-score: 0.537
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- 2e6 light chain (11 kDa, Protein from Mus musculus)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- Cryo-em structure of coxsackievirus b1 pre-a particle in complex with nab 2e6 (cvb1-pre-a:2e6) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 2E6 (CVB1-M:2E6)
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 7x2o
Q-score: 0.591
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- 2e6 light chain (11 kDa, Protein from Mus musculus)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- Palmitic acid (256 Da, Ligand)
- Cryo-em structure of coxsackievirus b1 mature virion in complex with nab 2e6 (cvb1-m:2e6) (Complex from Coxsackievirus B1)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 8A10 (CVB1-M:8A10)
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7x2t
Q-score: 0.531
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Palmitic acid (256 Da, Ligand)
- 8a10 heavy chain (13 kDa, Protein from Mus musculus)
- 8a10 light chain (11 kDa, Protein from Mus musculus)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Cryo-em structure of coxsackievirus b1 mature virion in complex with nab 8a10 (cvb1-m:8a10) (Complex from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 pre-A particle in complex with nAb 8A10 (CVB1-pre-A:8A10)
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 7x2w
Q-score: 0.56
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- 8a10 heavy chain (13 kDa, Protein from Mus musculus)
- 8a10 light chain (11 kDa, Protein from Mus musculus)
- Coxsackievirus b1 (Virus from Coxsackievirus B1)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 A particle in complex with nAb 2E6 (CVB1-A:2E6)
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 7x37
Q-score: 0.517
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- 2e6 light chain (11 kDa, Protein from Mus musculus)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- Cryo-em structure of coxsackievirus b1 a particle in complex with nab 2e6 (cvb1-a:2e6) (Complex from Coxsackievirus B1)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)