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Substrate-specific structural rearrangements of human Dicer
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW
Nat Struct Mol Biol (2013) 20 pp. 662-670 [ DOI: doi:10.1038/nsmb.2564 Pubmed: 23624860 ]
- Human dicer (220 kDa, Sample)
- Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
Substrate-specific structural rearrangements of human Dicer
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW
Nat Struct Mol Biol (2013) 20 pp. 662-670 [ DOI: doi:10.1038/nsmb.2564 Pubmed: 23624860 ]
- 35 bp pre-sirna (24 kDa, RNA from Homo sapiens)
- Human dicer in complex with a 35 bp pre-sirna (250 kDa, Sample)
- Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
Substrate-specific structural rearrangements of human Dicer
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW
Nat Struct Mol Biol (2013) 20 pp. 662-670 [ DOI: doi:10.1038/nsmb.2564 Pubmed: 23624860 ]
- Human dicer in complex with pre-let7 (250 kDa, Sample)
- Pre-let7 (24 kDa, Macromolecule from Homo sapiens)
- Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
Substrate-specific structural rearrangements of human Dicer
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW
Nat Struct Mol Biol (2013) 20 pp. 662-670 [ DOI: doi:10.1038/nsmb.2564 Pubmed: 23624860 ]
- Human dicer-pact heterodimer in closed conformation (260 kDa, Sample)
- Interferon-inducible double stranded rna-dependent protein kinase activator a (34 kDa, Protein from Homo sapiens)
- Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
Substrate-specific structural rearrangements of human Dicer
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW
Nat Struct Mol Biol (2013) 20 pp. 662-670 [ DOI: doi:10.1038/nsmb.2564 Pubmed: 23624860 ]
Substrate-specific structural rearrangements of human Dicer
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW
Nat Struct Mol Biol (2013) 20 pp. 662-670 [ DOI: doi:10.1038/nsmb.2564 Pubmed: 23624860 ]
- Interferon-inducible double stranded rna-dependent protein kinase activator a (34 kDa, Protein from Homo sapiens)
- Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
- Human dicer-pact heterodimer in open conformation (260 kDa, Sample)