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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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primary_citation_author:"Selmer M" AND author_name:"Larsson D"

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EMD-17363

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Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane in post-translocational state

Release date: May 1, 2024
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 8p2f
Q-score: 0.597

Gonzalez-Lopez A, Larsson D, Nelson B, Hergenrother PJ, Selmer M

To Be Published

Sample:

30s ribosomal protein s4 (23 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s6 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l29 (8 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l19 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l22 (12 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s10 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l33 1 (5 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s17 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l4 (22 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s5 (17 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s12 (15 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s13 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l25 (23 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l27 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
23s ribosomal rna (946 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s16 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
2-[(3~{r},4~{s},5~{s},8~{s},9~{s},10~{s},11~{r},13~{s},14~{s},16~{s})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid (546 Da, Ligand)
50s ribosomal protein l30 (6 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l32 (6 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l20 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s20 (9 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l24 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l36 (4 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s18 (9 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l21 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s11 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l31 type b (9 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Guanosine-5'-diphosphate (443 Da, Ligand)
50s ribosomal protein l35 (7 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Potassium ion (39 Da, Ligand)
50s ribosomal protein l17 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Zinc ion (65 Da, Ligand)
50s ribosomal protein l3 (23 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
16s ribosomal rna (503 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
1,4-diaminobutane (88 Da, Ligand)
50s ribosomal protein l18 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Spermidine (145 Da, Ligand)
50s ribosomal protein l23 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Staphylococcus aureus 70s ribosome with elongation factor g and fusidic acid cyclopentane (2 MDa, Complex from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s3 (24 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s14 type z (7 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Water (18 Da, Ligand)
50s ribosomal protein l2 (30 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l28 (6 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Mrna (7 kDa, RNA from Escherichia coli)
Magnesium ion (24 Da, Ligand)
5s ribosomal rna (36 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
Trna (24 kDa, RNA from Escherichia coli)
50s ribosomal protein l15 (15 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s2 (29 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s7 (17 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s8 (14 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Elongation factor g (76 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l5 (20 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s9 (14 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s15 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l16 (16 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l14 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s19 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l34 (5 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l6 (19 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l13 (16 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)

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EMD-17364

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Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane with a tRNA in pe/E chimeric hybrid state

Release date: May 1, 2024
Resolution: 2.02 Å
EM Method: Single-particle
Fitted PDBs: 8p2g
Q-score: 0.68

Gonzalez-Lopez A, Larsson D, Nelson B, Hergenrother PJ, Selmer M

To Be Published

Sample:

30s ribosomal protein s4 (23 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s6 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l22 (12 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l19 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l29 (8 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Large ribosomal subunit protein bl33a (5 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s17 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l4 (22 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s5 (17 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s12 (15 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s13 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l25 (23 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l27 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
23s ribosomal rna (946 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s16 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
2-[(3~{r},4~{s},5~{s},8~{s},9~{s},10~{s},11~{r},13~{s},14~{s},16~{s})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid (546 Da, Ligand)
50s ribosomal protein l20 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l30 (6 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s20 (9 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l24 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l36 (4 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s18 (9 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l21 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s11 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l31 type b (9 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Large ribosomal subunit protein bl32 (6 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Guanosine-5'-diphosphate (443 Da, Ligand)
50s ribosomal protein l35 (7 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l17 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Zinc ion (65 Da, Ligand)
50s ribosomal protein l3 (23 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
16s ribosomal rna (503 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
1,4-diaminobutane (88 Da, Ligand)
50s ribosomal protein l18 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Spermidine (145 Da, Ligand)
50s ribosomal protein l23 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Staphylococcus aureus 70s ribosome with elongation factor g and fusidic acid cyclopentane (2 MDa, Complex from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s3 (24 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s14 type z (7 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Small ribosomal subunit protein us10 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Water (18 Da, Ligand)
50s ribosomal protein l2 (30 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l28 (6 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Mrna (7 kDa, RNA from Escherichia coli)
Magnesium ion (24 Da, Ligand)
5s ribosomal rna (36 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l15 (15 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Trna (24 kDa, RNA from Escherichia coli)
30s ribosomal protein s2 (29 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s7 (17 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s8 (14 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Elongation factor g (76 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l5 (20 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s9 (14 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s15 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l16 (16 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l14 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s19 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l34 (5 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l6 (19 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l13 (16 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)

[Show more]

EMD-17365

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Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid with a tRNA in pe/E chimeric state

Release date: May 1, 2024
Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 8p2h
Q-score: 0.6

Gonzalez-Lopez A, Larsson D, Nelson B, Hergenrother PJ, Selmer M

To Be Published

Sample:

30s ribosomal protein s4 (23 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s6 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l22 (12 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l19 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l29 (8 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Large ribosomal subunit protein bl33a (5 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s17 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l4 (22 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s5 (17 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s12 (15 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s13 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l25 (23 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l27 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
23s ribosomal rna (946 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s16 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l20 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l30 (6 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s20 (9 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l24 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l36 (4 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s18 (9 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l21 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s11 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l31 type b (9 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Large ribosomal subunit protein bl32 (6 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Guanosine-5'-diphosphate (443 Da, Ligand)
50s ribosomal protein l35 (7 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l17 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Staphylococcus aureus 70s ribosome with elongation factor g and fusidic acid (2 MDa, Complex from Staphylococcus aureus subsp. aureus NCTC 8325)
Zinc ion (65 Da, Ligand)
50s ribosomal protein l3 (23 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
16s ribosomal rna (503 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
1,4-diaminobutane (88 Da, Ligand)
50s ribosomal protein l18 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Spermidine (145 Da, Ligand)
Fusidic acid (516 Da, Ligand)
50s ribosomal protein l23 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s3 (24 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s14 type z (7 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Small ribosomal subunit protein us10 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l2 (30 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l28 (6 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Mrna (7 kDa, RNA from Escherichia coli)
Magnesium ion (24 Da, Ligand)
5s ribosomal rna (36 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l15 (15 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Trna (24 kDa, RNA from Escherichia coli)
30s ribosomal protein s2 (29 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s7 (17 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s8 (14 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Elongation factor g (76 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l5 (20 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s9 (14 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s15 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l16 (16 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l14 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
30s ribosomal protein s19 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l34 (5 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l6 (19 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
50s ribosomal protein l13 (16 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)

[Show more]

Sort by: Download

Showing 1 - 3 of 3. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [3]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

Field: