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Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8c6d
Q-score: 0.614
Kingston NJ, Snowden JS, Martyna A, Shegdar M, Grehan K, Tedcastle A, Pegg E, Fox H, Macadam AJ, Martin J, Hogle JM, Rowlands DJ, Stonehouse NJ
bioRxiv (2023) [ DOI: doi:10.1101/2023.01.30.526315 Pubmed: 36778240 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Genome polyprotein (26 kDa, Protein from Enterovirus A71)
- (2s,3r,4e)-2-aminooctadec-4-ene-1,3-diol (299 Da, Ligand)
- Genome polyprotein (32 kDa, Protein from Enterovirus A71)
- Genome polyprotein (fragment) (35 kDa, Protein from Enterovirus A71)
VelcroVax tandem HBcAg with SUMO-Affimer inserted at MIR (T=4 VLP)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7zq8
Q-score: 0.612
Kingston NJ, Grehan K, Snowden JS, Hassall M, Alzahrani J, Paesen GC, Sherry L, Hayward C, Roe A, Stephen S, Tomlinson D, Zeltina A, Doores KJ, Ranson NA, Stacey M, Page M, Rose NJ, Bowden TA, Rowlands DJ, Stonehouse NJ
mSphere (2023) 8 pp. e0056822-e0056822 [ Pubmed: 36719225 DOI: doi:10.1128/msphere.00568-22 ]
VelcroVax tandem HBcAg with SUMO-Affimer inserted at MIR (T=3* VLP)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7zqa
Q-score: 0.513
Kingston NJ, Grehan K, Snowden JS, Hassall M, Alzahrani J, Paesen GC, Sherry L, Hayward C, Roe A, Stephen S, Tomlinson D, Zeltina A, Doores KJ, Ranson NA, Stacey M, Page M, Rose NJ, Bowden TA, Rowlands DJ, Stonehouse NJ
mSphere (2023) 8 pp. e0056822-e0056822 [ Pubmed: 36719225 DOI: doi:10.1128/msphere.00568-22 ]
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8ayx
Q-score: 0.649
Bahar MW, Nasta V, Fox H, Sherry L, Grehan K, Porta C, Macadam AJ, Stonehouse NJ, Rowlands DJ, Fry EE, Stuart DI
Commun Biol (2022) 5 pp. 1293-1293 [ DOI: doi:10.1038/s42003-022-04252-5 Pubmed: 36434067 ]
- Human poliovirus 3 (5 MDa, Virus from Human poliovirus 3)
- Capsid protein, vp0 (37 kDa, Protein from Human poliovirus 3)
- Glutathione (307 Da, Ligand)
- 1-[(3s)-5-[4-[(e)-ethoxyiminomethyl]phenoxy]-3-methyl-pentyl]-3-pyridin-4-yl-imidazolidin-2-one (410 Da, Ligand)
- Capsid protein, vp1 (33 kDa, Protein from Human poliovirus 3)
- Capsid protein, vp3 (26 kDa, Protein from Human poliovirus 3)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8ayy
Q-score: 0.647
Bahar MW, Nasta V, Fox H, Sherry L, Grehan K, Porta C, Macadam AJ, Stonehouse NJ, Rowlands DJ, Fry EE, Stuart DI
Commun Biol (2022) 5 pp. 1293-1293 [ DOI: doi:10.1038/s42003-022-04252-5 Pubmed: 36434067 ]
- Human poliovirus 3 (5 MDa, Virus from Human poliovirus 3)
- Capsid protein, vp0 (37 kDa, Protein from Human poliovirus 3)
- Glutathione (307 Da, Ligand)
- 3-{3,5-dimethyl-4-[3-(3-methyl-isoxazol-5-yl)-propoxy]-phenyl}-5-trifluoromethyl-[1,2,4]oxadiazole (381 Da, Ligand)
- Capsid protein, vp1 (33 kDa, Protein from Human poliovirus 3)
- Capsid protein, vp3 (26 kDa, Protein from Human poliovirus 3)
Poliovirus type 3 (strain Saukett) stabilised virus-like particle (PV3 SC8).
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8anw
Q-score: 0.62
Sherry L, Grehan K, Swanson JJ, Bahar MW, Porta C, Fry EE, Stuart DI, Rowlands DJ, Stonehouse NJ
Viruses (2022) 14 [ DOI: doi:10.3390/v14102159 Pubmed: 36298714 ]
- Human poliovirus 3 (5 MDa, Virus from Human poliovirus 3)
- Capsid protein, vp0 (37 kDa, Protein from Human poliovirus 3)
- Capsid protein, vp3 (26 kDa, Protein from Human poliovirus 3)
- Capsid protein, vp1 (33 kDa, Protein from Human poliovirus 3)
- Sphingosine (299 Da, Ligand)
Cryo-EM structure of fatty acid synthase (FAS) from Pichia pastoris
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7bc4
Q-score: 0.551
Snowden JS, Alzahrani J, Sherry L, Stacey M, Rowlands DJ, Ranson NA, Stonehouse NJ
Sci Rep (2021) 11 pp. 9773-9773 [ DOI: doi:10.1038/s41598-021-89196-2 Pubmed: 33963233 ]
- Flavin mononucleotide (456 Da, Ligand)
- Fatty acid synthase subunit alpha (206 kDa, Protein from Yeast)
- Fatty acid synthase subunit beta (230 kDa, Protein from Yeast)
- Fatty acid synthase (2 MDa, Complex from Komagataella phaffii GS115)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7bc5
Q-score: 0.381
Snowden JS, Alzahrani J, Sherry L, Stacey M, Rowlands DJ, Ranson NA, Stonehouse NJ
Sci Rep (2021) 11 pp. 9773-9773 [ DOI: doi:10.1038/s41598-021-89196-2 Pubmed: 33963233 ]
- Fatty acid synthase subunit alpha (206 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Fatty acid synthase (2 MDa, Complex from Komagataella phaffii GS115)
Resolution: 2.23 Å
EM Method: Single-particle
Fitted PDBs: 6thd
Q-score: 0.738
Chandler-Bostock R, Mata CP, Bingham RJ, Dykeman EC, Meng B, Tuthill TJ, Rowlands DJ, Ranson NA, Twarock R, Stockley PG
PLoS Pathog (2020) 16 pp. e1009146-e1009146 [ Pubmed: 33370422 DOI: doi:10.1371/journal.ppat.1009146 ]
- Genome polyprotein (27 kDa, Protein from Bovine enterovirus (strain VG-5-27))
- Myristic acid (228 Da, Ligand)
- Sulfate ion (96 Da, Ligand)
- Genome polyprotein (31 kDa, Protein from Bovine enterovirus (strain VG-5-27))
- Bovine enterovirus (strain vg-5-27) (Virus from Bovine enterovirus (strain VG-5-27))
- Water (18 Da, Ligand)
- Genome polyprotein (26 kDa, Protein from Bovine enterovirus (strain VG-5-27))
- Genome polyprotein (5 kDa, Protein from Bovine enterovirus (strain VG-5-27))
Chandler-Bostock R, Mata CP, Bingham RJ, Dykeman EC, Meng B, Tuthill TJ, Rowlands DJ, Ranson NA, Twarock R, Stockley PG
PLoS Pathog (2020) 16 pp. e1009146-e1009146 [ Pubmed: 33370422 DOI: doi:10.1371/journal.ppat.1009146 ]
- Bovine enterovirus 1 vp4 (Protein from Bovine enterovirus type 1)
- Bovine enterovirus 1 vp2 (Protein from Bovine enterovirus type 1)
- Bovine enterovirus type 1 (Virus from Bovine enterovirus type 1)
- Bovine enterovirus 1 vp3 (Protein from Bovine enterovirus type 1)
- Bovine enterovirus 1 vp1 (Protein from Bovine enterovirus type 1)