Cryo-EM structure of human disease-associated P301L Tau amyloid fibril from mouse brain
Zhao W, Liu K, Fan Y, Zhao Q, Tao Y, Zhang M, Gan L, Yu W, Sun B, Li D, Liu C, Wang J
Cell Discov (2024) 10 pp. 27-27 [ Pubmed: 38448404 DOI: doi:10.1038/s41421-023-00637-w ]
- Island a (783 Da, Protein from Mus musculus)
- P301l tau amyloid fibril from rtg4510 mice (40 kDa, Protein from Mus musculus)
- Tau (Tissue from Mus musculus)
- Island b (869 Da, Protein from Mus musculus)
Cryo-EM structure of human alpha-fetoprotein
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 8x1n
Q-score: 0.518
Liu K, Wu C, Zhu M, Xu J, Lin B, Lin H, Liu Z, Li M
Commun Biol (2024) 7 pp. 505-505 [ Pubmed: 38678117 DOI: doi:10.1038/s42003-024-06219-0 ]
- Zinc ion (65 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- Alpha-fetoprotein (68 kDa, Protein from Homo sapiens)
- Cryo-em structure of human alpha-fetoprotein (Complex from Homo sapiens)
Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with hippopotamus ACE2
Resolution: 2.62 Å
EM Method: Single-particle
Fitted PDBs: 8wlo
Q-score: 0.429
Yang R, Han P, Han P, Li D, Zhao R, Niu S, Liu K, Li S, Tian WX, Gao GF
J Virol (2024) 98 pp. e0045124-e0045124 [ Pubmed: 38591877 DOI: doi:10.1128/jvi.00451-24 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 prototype spike protein in complex with hippopotamus ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme (69 kDa, Protein from Hippopotamus amphibius)
- Zinc ion (65 Da, Ligand)
- Spike glycoprotein (135 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 8wlr
Q-score: 0.553
Yang R, Han P, Han P, Li D, Zhao R, Niu S, Liu K, Li S, Tian WX, Gao GF
J Virol (2024) 98 pp. e0045124-e0045124 [ Pubmed: 38591877 DOI: doi:10.1128/jvi.00451-24 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Angiotensin-converting enzyme (69 kDa, Protein from Hippopotamus amphibius)
- Sars-cov-2 prototype spike protein receptor-binding domain in complex with hippopotamus ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Spike glycoprotein (135 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with golden hamster ACE2 (local refinement)
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8ka8
Q-score: 0.486
Niu S, Zhao Z, Liu Z, Rong X, Chai Y, Bai B, Han P, Shang G, Ren J, Wang Y, Zhao X, Liu K, Tian WX, Wang Q, Gao GF
J Virol (2024) 98 pp. e0115723-e0115723 [ DOI: doi:10.1128/jvi.01157-23 Pubmed: 38305152 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Delta rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Golden hamster angiotensin-converting enzyme 2 (Complex from Mesocricetus auratus)
- Cryo-em structure of sars-cov-2 delta rbd in complex with golden hamster ace2 (local refinement) (Complex)
- Angiotensin-converting enzyme (68 kDa, Protein from Mesocricetus auratus)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 BA.3 RBD in complex with golden hamster ACE2 (local refinement)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8kc2
Q-score: 0.556
Niu S, Zhao Z, Liu Z, Rong X, Chai Y, Bai B, Han P, Shang G, Ren J, Wang Y, Zhao X, Liu K, Tian WX, Wang Q, Gao GF
J Virol (2024) 98 pp. e0115723-e0115723 [ DOI: doi:10.1128/jvi.01157-23 Pubmed: 38305152 ]
- Cryo-em structure of sars-cov-2 ba.3 rbd in complex with golden hamster ace2 (local refinement) (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Golden hamster angiotensin-converting enzyme 2 (Complex from Mesocricetus auratus)
- Angiotensin-converting enzyme (68 kDa, Protein from Mesocricetus auratus)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Ba.3 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of human NTCP-myr-preS1-YN9048Fab complex
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 8hrx
Q-score: 0.523
Asami J, Park JH, Nomura Y, Kobayashi C, Mifune J, Ishimoto N, Uemura T, Liu K, Sato Y, Zhang Z, Muramatsu M, Wakita T, Drew D, Iwata S, Shimizu T, Watashi K, Park SY, Nomura N, Ohto U
Nat Struct Mol Biol (2024) 31 pp. 447-454 [ Pubmed: 38233573 DOI: doi:10.1038/s41594-023-01191-5 ]
- Ntcp-myr-pres1-yn9048fab (Complex from Homo sapiens)
- Fab light chain from antibody igg clone number yn9048 (23 kDa, Protein from Ondatra zibethicus)
- Sodium/bile acid cotransporter (38 kDa, Protein from Homo sapiens)
- Fab heavy chain from antibody igg clone number yn9048 (26 kDa, Protein from Ondatra zibethicus)
- Pres1 protein (fragment) (6 kDa, Protein from Hepatitis B virus)
Cryo-EM structure of human NTCP-myr-preS1-YN9016Fab complex
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 8hry
Q-score: 0.523
Asami J, Park JH, Nomura Y, Kobayashi C, Mifune J, Ishimoto N, Uemura T, Liu K, Sato Y, Zhang Z, Muramatsu M, Wakita T, Drew D, Iwata S, Shimizu T, Watashi K, Park SY, Nomura N, Ohto U
Nat Struct Mol Biol (2024) 31 pp. 447-454 [ Pubmed: 38233573 DOI: doi:10.1038/s41594-023-01191-5 ]
- Fab heavy chain from antibody igg clone number yn9016 (25 kDa, Protein from Ondatra zibethicus)
- Ntcp-myr-pres1-yn9016fab (Complex from Homo sapiens)
- Fab light chain from antibody igg clone number yn9016 (23 kDa, Protein from Ondatra zibethicus)
- Large s protein (fragment) (6 kDa, Protein from Hepatitis B virus)
- Sodium/bile acid cotransporter (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of ATP13A2 in the E1-ATP state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8iek
Q-score: 0.377
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Magnesium ion (24 Da, Ligand)
- Cryo-em structure of atp13a2 in the e1-atp state (Complex from Homo sapiens)
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Cryo-EM structure of ATP13A2 in the E1-like state
Resolution: 5.65 Å
EM Method: Single-particle
Fitted PDBs: 8iel
Q-score: 0.229