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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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primary_citation_author:"Lin J" AND author_name:"Huang Q"

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EMD-10102

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Type III-B Cmr-beta Cryo-EM structure of the Apo state

Release date: July 8, 2020
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 6s6b
Q-score: 0.456

Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J, Huang Q, Li Y, She Q, Montoya G

Mol Cell (2020) 79 pp. 741-757.e7 [ DOI: doi:10.1016/j.molcel.2020.07.008 Pubmed: 32730741 ]

Sample:

Cmr1 (55 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr2 family (120 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Crispr-associated ramp protein, cmr4 family (32 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Crispr-associated protein, cmr3 family (36 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Crrna (51-mer) (16 kDa, RNA from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr5 family (17 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Type iii-b cmr-beta binary complex, crrna-bound (900 kDa, Complex from Sulfolobus islandicus REY15A)
Crispr-associated protein cmrx (19 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Zinc ion (65 Da, Ligand)
Crispr-associated ramp protein, cmr6 family (33 kDa, Protein from Sulfolobus islandicus (strain REY15A))

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EMD-10117

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Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 1

Release date: July 8, 2020
Resolution: 2.41 Å
EM Method: Single-particle
Fitted PDBs: 6s8b
Q-score: 0.48

Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J, Huang Q, Li Y, She Q, Montoya G

Mol Cell (2020) 79 pp. 741-757.e7 [ DOI: doi:10.1016/j.molcel.2020.07.008 Pubmed: 32730741 ]

Sample:

Cmr1 (55 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr2 family (120 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Crispr-associated protein, cmr3 family (36 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Crispr-associated protein cmrx (19 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Manganese (ii) ion (54 Da, Ligand)
Crispr-associated ramp protein, cmr4 family (32 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Crrna (16 kDa, RNA from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr5 family (17 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Cognate target rna (46-mer) (14 kDa, RNA from Sulfolobus islandicus REY15A)
Type iii-b cmr-beta ternary complex, cognate target rna and amppnp bound (900 kDa, Complex from Sulfolobus islandicus REY15A)
Zinc ion (65 Da, Ligand)
Crispr-associated ramp protein, cmr6 family (33 kDa, Protein from Sulfolobus islandicus (strain REY15A))

[Show more]

EMD-10119

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Cryo-EM structure of the type III-B Cmr-beta complex bound to non-cognate target RNA

Release date: July 8, 2020
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6s8e
Q-score: 0.397

Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J, Huang Q, Li Y, She Q, Montoya G

Mol Cell (2020) 79 pp. 741-757.e7 [ DOI: doi:10.1016/j.molcel.2020.07.008 Pubmed: 32730741 ]

Sample:

Non-cognate target rna (15 kDa, RNA from synthetic construct)
Crispr-associated protein cmr7 (19 kDa, Protein from Sulfolobus islandicus REY15A)
Crrna (16 kDa, RNA from Sulfolobus islandicus REY15A)
Crispr-associated ramp protein, cmr4 family (32 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr2 family (120 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr3 family (36 kDa, Protein from Sulfolobus islandicus REY15A)
Type iii-b cmr-beta complex bound to non-cognate target rna (900 kDa, Complex from Sulfolobus islandicus REY15A)
Cmr1,crispr-associated ramp protein, cmr1 family,crispr-associated ramp protein, cmr1 family (55 kDa, Protein from Sulfolobus islandicus REY15A)
Zinc ion (65 Da, Ligand)
Crispr-associated ramp protein, cmr6 family (33 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr5 family (17 kDa, Protein from Sulfolobus islandicus REY15A)

[Show more]

EMD-10126

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Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 2

Release date: July 8, 2020
Resolution: 2.68 Å
EM Method: Single-particle
Fitted PDBs: 6s91
Q-score: 0.463

Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J, Huang Q, Li Y, She Q, Montoya G

Mol Cell (2020) 79 pp. 741-757.e7 [ DOI: doi:10.1016/j.molcel.2020.07.008 Pubmed: 32730741 ]

Sample:

Cmr1,crispr-associated ramp protein, cmr1 family (55 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Crispr-associated protein, cmr2 family (120 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Cognate target rna (Complex from synthetic construct)
Crrna (48-mer) (16 kDa, RNA from Sulfolobus islandicus REY15A)
Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Crispr-associated protein, cmr3 family (36 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Cognate target rna (14 kDa, RNA from synthetic construct)
Manganese (ii) ion (54 Da, Ligand)
Crispr-associated ramp protein, cmr4 family (32 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Crispr-associated protein, cmr5 family (17 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Crispr-associated ramp proteins cmr4 and cmr6, and crrna (Complex from Sulfolobus islandicus REY15A)
Crispr-associated protein cmrx (19 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Zinc ion (65 Da, Ligand)
Crispr-associated ramp protein, cmr6 family (33 kDa, Protein from Sulfolobus islandicus (strain REY15A))
Crispr-associated proteins cmr5, cmr3, cmr1, cmr2, cmr7 (Complex from Sulfolobus islandicus REY15A)
Type iii-b cmr-beta ternary complex, cognate target rna and amppnp bound (900 kDa, Complex)

[Show more]

EMD-10196

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Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 2, in the presence of ssDNA

Release date: July 8, 2020
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 6sh8
Q-score: 0.437

Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J, Huang Q, Li Y, She Q, Montoya G

Mol Cell (2020) 79 pp. 741-757.e7 [ DOI: doi:10.1016/j.molcel.2020.07.008 Pubmed: 32730741 ]

Sample:

Cognate target rna (14 kDa, RNA from synthetic construct)
Crrna (Complex from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr3 family (36 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr3 family (Complex from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr5 family (17 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated protein cmrx (Complex from Sulfolobus islandicus REY15A)
Crrna (16 kDa, RNA from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr2 family (120 kDa, Protein from Sulfolobus islandicus REY15A)
Zinc ion (65 Da, Ligand)
Crispr-associated protein cmrx (19 kDa, Protein from Sulfolobus islandicus REY15A)
Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Cmr1,crispr-associated ramp protein, cmr1 family (55 kDa, Protein from Sulfolobus islandicus REY15A)
Manganese (ii) ion (54 Da, Ligand)
Crispr-associated ramp protein, cmr4 family (32 kDa, Protein from Sulfolobus islandicus REY15A)
Type iii-b cmr-beta ternary complex, cognate target rna and amppnp bound, in the presence of ssdna (900 kDa, Complex)
Crispr-associated ramp protein, cmr6 family (Complex from Sulfolobus islandicus REY15A)
Crispr-associated ramp protein, cmr6 family (33 kDa, Protein from Sulfolobus islandicus REY15A)
Cognate target rna (Complex from synthetic construct)
Crispr-associated ramp protein, cmr4 family (Complex from Sulfolobus islandicus REY15A)
Cmr1,crispr-associated ramp protein, cmr1 family (Complex from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr5 family (Complex from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr2 family (Complex from Sulfolobus islandicus REY15A)

[Show more]

EMD-10197

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Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 1, in the presence of ssDNA

Release date: July 8, 2020
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 6shb
Q-score: 0.442

Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J, Huang Q, Li Y, She Q, Montoya G

Mol Cell (2020) 79 pp. 741-757.e7 [ DOI: doi:10.1016/j.molcel.2020.07.008 Pubmed: 32730741 ]

Sample:

Crispr-associated protein, cmr3 family (36 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr3 family (Complex from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr5 family (17 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated protein cmrx (Complex from Sulfolobus islandicus REY15A)
Crrna (49-mer) (16 kDa, RNA from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr2 family (120 kDa, Protein from Sulfolobus islandicus REY15A)
Crrna (49-mer) (Complex from Sulfolobus islandicus REY15A)
Zinc ion (65 Da, Ligand)
Crispr-associated protein cmrx (19 kDa, Protein from Sulfolobus islandicus REY15A)
Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Cognate target rna (43-mer) (14 kDa, RNA from synthetic construct)
Cmr1,crispr-associated ramp protein, cmr1 family (55 kDa, Protein from Sulfolobus islandicus REY15A)
Manganese (ii) ion (54 Da, Ligand)
Cognate target rna (43-mer) (Complex from synthetic construct)
Crispr-associated ramp protein, cmr4 family (32 kDa, Protein from Sulfolobus islandicus REY15A)
Type iii-b cmr-beta ternary complex, cognate target rna and amppnp bound, in the presence of ssdna (900 kDa, Complex)
Crispr-associated ramp protein, cmr6 family (Complex from Sulfolobus islandicus REY15A)
Crispr-associated ramp protein, cmr6 family (33 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated ramp protein, cmr4 family (Complex from Sulfolobus islandicus REY15A)
Cmr1,crispr-associated ramp protein, cmr1 family (Complex from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr5 family (Complex from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr2 family (Complex from Sulfolobus islandicus REY15A)

[Show more]

EMD-10209

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Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA

Release date: July 8, 2020
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 6sic
Q-score: 0.343

Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J, Huang Q, Li Y, She Q, Montoya G

Mol Cell (2020) 79 pp. 741-757.e7 [ DOI: doi:10.1016/j.molcel.2020.07.008 Pubmed: 32730741 ]

Sample:

Crispr-associated protein cmrx (19 kDa, Protein from Sulfolobus islandicus REY15A)
Type iii-b cmr-beta binary complex, crrna-bound (Complex from Sulfolobus islandicus REY15A)
Type iii-b cmr-beta binary complex, crrna-bound (900 kDa, Complex)
Crispr-associated ramp protein, cmr1 family (55 kDa, Protein from Sulfolobus islandicus REY15A)
Crrna (16 kDa, RNA from Sulfolobus islandicus REY15A)
Crispr-associated ramp protein, cmr4 family (32 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr2 family (120 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr3 family (36 kDa, Protein from Sulfolobus islandicus REY15A)
Cognate target rna (14 kDa, RNA from Sulfolobus islandicus REY15A)
Zinc ion (65 Da, Ligand)
Crispr-associated ramp protein, cmr6 family (33 kDa, Protein from Sulfolobus islandicus REY15A)
Crispr-associated protein, cmr5 family (17 kDa, Protein from Sulfolobus islandicus REY15A)

[Show more]

Sort by: Download

Showing 1 - 7 of 7. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [7]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

Field: