SARS-CoV-2 RBD in complex with A5-10 Fab and A34-2 Fab
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7f3q
Q-score: 0.482
Dou Y, Xu K, Deng YQ, Jia Z, Lan J, Xu X, Zhang G, Cao T, Liu P, Wang X, Wang X, Xu L, Du P, Qin CF, Liu H, Li Y, Wu G, Wang K, Lu B
Antib Ther (2023) 6 pp. 76-86 [ DOI: doi:10.1093/abt/tbad002 Pubmed: 37077472 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 s protein rbd in complex with two fabs (Complex)
- Heavy chain of a34-2 fab (23 kDa, Protein from Homo sapiens)
- Light chain of a5-10 fab (22 kDa, Protein from Homo sapiens)
- Fab (Complex from Homo sapiens)
- Sars-cov-2 s protein rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of a34-2 fab (22 kDa, Protein from Homo sapiens)
- 2-(n-morpholino)-ethanesulfonic acid (195 Da, Ligand)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of a5-10 fab (24 kDa, Protein from Homo sapiens)
Cryo-EM structure of SARS-CoV2 RBD-ACE2 complex
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7dqa
Q-score: 0.508
Liu N, Zheng LM, Xu J, Wang J, Hu CX, Lan J, Zhang X, Zhang JC, Xu K, Cheng H, Yang Z, Gao X, Wang XQ, Peng HL, Chen YN, Wang HW
Biophys Rep (2022) 7 pp. 227-238 [ DOI: doi:10.52601/bpr.2021.210007 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of sars-cov2 rbd-ace2 complex (95 kDa, Complex from Homo sapiens)
- Ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Chloride ion (35 Da, Ligand)
- Sars-cov2 rbd (Complex)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Spike glycoprotein (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
S protein of SARS-CoV-2 in complex bound with P36-5D2(state2)
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 7fae
Q-score: 0.292
Shan S, Mok CK, Zhang S, Lan J, Li J, Yang Z, Wang R, Cheng L, Fang M, Aw ZQ, Yu J, Zhang Q, Shi X, Zhang T, Zhang Z, Wang J, Wang X, Chu JJH, Zhang L
Front Immunol (2021) 12 pp. 766821-766821 [ DOI: doi:10.3389/fimmu.2021.766821 Pubmed: 34966387 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S protein of sars-cov-2 in complex bound with p36-5d2 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- P36-5d2 heavy chain (51 kDa, Protein from Homo sapiens)
- S protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (143 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- P36-5d2 antibody fab (Complex)
- P36-5d2 light chain (25 kDa, Protein from Homo sapiens)
S protein of SARS-CoV-2 in complex bound with P36-5D2 (state1)
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7faf
Q-score: 0.258
Shan S, Mok CK, Zhang S, Lan J, Li J, Yang Z, Wang R, Cheng L, Fang M, Aw ZQ, Yu J, Zhang Q, Shi X, Zhang T, Zhang Z, Wang J, Wang X, Chu JJH, Zhang L
Front Immunol (2021) 12 pp. 766821-766821 [ DOI: doi:10.3389/fimmu.2021.766821 Pubmed: 34966387 ]
- S protein of sars-cov-2 in complex bound with p36-5d2 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- P36-5d2 fab (Complex)
- P36-5d2 heavy chain (51 kDa, Protein from Homo sapiens)
- S protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (143 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- P36-5d2 light chain (25 kDa, Protein from Homo sapiens)
SARS-COV-2 Spike RBDMACSp6 binding to hACE2
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7fdg
Q-score: 0.364
Sun S, Gu H, Cao L, Chen Q, Ye Q, Yang G, Li RT, Fan H, Deng YQ, Song X, Qi Y, Li M, Lan J, Feng R, Guo Y, Zhu N, Qin S, Wang L, Zhang YF, Zhou C, Zhao L, Chen Y, Shen M, Cui Y, Yang X, Wang X, Tan W, Wang H, Wang X, Qin CF
Nat Commun (2021) 12 pp. 5654-5654 [ Pubmed: 34580297 DOI: doi:10.1038/s41467-021-25903-x ]
- Angiotensin-converting enzyme 2 (71 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (24 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike rbdmacsp6-hace2 complex (Complex from Severe acute respiratory syndrome coronavirus 2)