YPEL5-bound WDR26-CTLH E3 ligase - assembly I
Gottemukkala KV, Chrustowicz J, Sherpa D, Sepic S, Vu DT, Karayel O, Papadopoulou EC, Gross A, Schorpp K, von Gronau S, Hadian K, Murray PJ, Mann M, Schulman BA, Alpi AF
Mol Cell (2024) 84 pp. 1948-1963.e11 [ Pubmed: 38759627 DOI: doi:10.1016/j.molcel.2024.04.014 ]
- Complex of human wdr26-ctlh e3 ligase bound to ypel5 (900 kDa, Complex from Homo sapiens)
YPEL5-bound WDR26-CTLH E3 ligase - assembly II
Gottemukkala KV, Chrustowicz J, Sherpa D, Sepic S, Vu DT, Karayel O, Papadopoulou EC, Gross A, Schorpp K, von Gronau S, Hadian K, Murray PJ, Mann M, Schulman BA, Alpi AF
Mol Cell (2024) 84 pp. 1948-1963.e11 [ Pubmed: 38759627 DOI: doi:10.1016/j.molcel.2024.04.014 ]
- Complex of human wdr26-ctlh e3 ligase bound to ypel5 (900 kDa, Complex from Homo sapiens)
NMNAT1 core-bound RANBP9-TWA1-WDR26 module of WDR26-CTLH E3 ligase
Gottemukkala KV, Chrustowicz J, Sherpa D, Sepic S, Vu DT, Karayel O, Papadopoulou EC, Gross A, Schorpp K, von Gronau S, Hadian K, Murray PJ, Mann M, Schulman BA, Alpi AF
Mol Cell (2024) 84 pp. 1948-1963.e11 [ Pubmed: 38759627 DOI: doi:10.1016/j.molcel.2024.04.014 ]
NMNAT1 loop-bound RANBP9-TWA1-WDR26 module of WDR26-CTLH E3 ligase
Gottemukkala KV, Chrustowicz J, Sherpa D, Sepic S, Vu DT, Karayel O, Papadopoulou EC, Gross A, Schorpp K, von Gronau S, Hadian K, Murray PJ, Mann M, Schulman BA, Alpi AF
Mol Cell (2024) 84 pp. 1948-1963.e11 [ Pubmed: 38759627 DOI: doi:10.1016/j.molcel.2024.04.014 ]
NMNAT1-bound WDR26-CTLH E3 ligase assembly I - class 1
Gottemukkala KV, Chrustowicz J, Sherpa D, Sepic S, Vu DT, Karayel O, Papadopoulou EC, Gross A, Schorpp K, von Gronau S, Hadian K, Murray PJ, Mann M, Schulman BA, Alpi AF
Mol Cell (2024) 84 pp. 1948-1963.e11 [ Pubmed: 38759627 DOI: doi:10.1016/j.molcel.2024.04.014 ]
NMNAT1-bound WDR26-CTLH E3 ligase assembly I - class 2
Gottemukkala KV, Chrustowicz J, Sherpa D, Sepic S, Vu DT, Karayel O, Papadopoulou EC, Gross A, Schorpp K, von Gronau S, Hadian K, Murray PJ, Mann M, Schulman BA, Alpi AF
Mol Cell (2024) 84 pp. 1948-1963.e11 [ Pubmed: 38759627 DOI: doi:10.1016/j.molcel.2024.04.014 ]
NMNAT1-bound WDR26-CTLH E3 ligase assembly II - class 1
Gottemukkala KV, Chrustowicz J, Sherpa D, Sepic S, Vu DT, Karayel O, Papadopoulou EC, Gross A, Schorpp K, von Gronau S, Hadian K, Murray PJ, Mann M, Schulman BA, Alpi AF
Mol Cell (2024) 84 pp. 1948-1963.e11 [ Pubmed: 38759627 DOI: doi:10.1016/j.molcel.2024.04.014 ]
NMNAT1-bound WDR26-CTLH E3 ligase assembly II - class 2
Gottemukkala KV, Chrustowicz J, Sherpa D, Sepic S, Vu DT, Karayel O, Papadopoulou EC, Gross A, Schorpp K, von Gronau S, Hadian K, Murray PJ, Mann M, Schulman BA, Alpi AF
Mol Cell (2024) 84 pp. 1948-1963.e11 [ Pubmed: 38759627 DOI: doi:10.1016/j.molcel.2024.04.014 ]
NMNAT1-bound WDR26-CTLH E3 ligase assembly II - class 3
Gottemukkala KV, Chrustowicz J, Sherpa D, Sepic S, Vu DT, Karayel O, Papadopoulou EC, Gross A, Schorpp K, von Gronau S, Hadian K, Murray PJ, Mann M, Schulman BA, Alpi AF
Mol Cell (2024) 84 pp. 1948-1963.e11 [ Pubmed: 38759627 DOI: doi:10.1016/j.molcel.2024.04.014 ]
Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to YPEL5
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8qbn
Q-score: 0.581
Gottemukkala KV, Chrustowicz J, Sherpa D, Sepic S, Vu DT, Karayel O, Papadopoulou EC, Gross A, Schorpp K, von Gronau S, Hadian K, Murray PJ, Mann M, Schulman BA, Alpi AF
Mol Cell (2024) 84 pp. 1948-1963.e11 [ Pubmed: 38759627 DOI: doi:10.1016/j.molcel.2024.04.014 ]
- Protein yippee-like 5 (13 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Complex of human wdr26-ctlh e3 ligase bound to ypel5 (900 kDa, Complex from Homo sapiens)
- Wd repeat-containing protein 26 (70 kDa, Protein from Homo sapiens)