EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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primary_citation_author:"Griffin PR" AND author_orcid:"0000-0002-8124-7472"

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EMDB [3]

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EMD-9013

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EsCas13d-crRNA binary complex

Release date: Oct. 3, 2018
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6e9e
Q-score: 0.494

Zhang C, Konermann S, Brideau NJ, Lotfy P, Wu X, Novick SJ, Strutzenberg T, Griffin PR, Hsu PD, Lyumkis D

Cell (2018) 175 pp. 212-223.e17 [ Pubmed: 30241607 DOI: doi:10.1016/j.cell.2018.09.001 ]

Sample:

Binary complex of escas13d with crrna and mg2+ (125 kDa, Complex from unidentified bacterium)
Magnesium ion (24 Da, Ligand)
Crrna (52-mer) (16 kDa, RNA from bacterium)
Escas13d (110 kDa, Protein from [Eubacterium] siraeum DSM 15702)

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EMD-9014

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EsCas13d-crRNA-target RNA ternary complex

Release date: Oct. 3, 2018
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6e9f
Q-score: 0.45

Zhang C, Konermann S, Brideau NJ, Lotfy P, Wu X, Novick SJ, Strutzenberg T, Griffin PR, Hsu PD, Lyumkis D

Cell (2018) 175 pp. 212-223.e17 [ Pubmed: 30241607 DOI: doi:10.1016/j.cell.2018.09.001 ]

Sample:

Rna (27-mer) (8 kDa, RNA from bacterium)
Crrna (52-mer) (16 kDa, RNA from bacterium)
Ternary complex of escas13d(r295a/h300a/r849a/h854a) with crrna, target rna and mg2+ (135 kDa, Complex from unidentified bacterium)
Escas13d (110 kDa, Protein from [Eubacterium] siraeum DSM 15702)
Magnesium ion (24 Da, Ligand)

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EMD-9015

Download Map 3D View Raw data

Release date: Oct. 3, 2018
Resolution: 6.5 Å
EM Method: Single-particle

Zhang C, Konermann S, Brideau NJ, Lotfy P, Wu X, Novick SJ, Strutzenberg T, Griffin PR, Hsu PD, Lyumkis D

Cell (2018) 175 pp. 212-223.e17 [ Pubmed: 30241607 DOI: doi:10.1016/j.cell.2018.09.001 ]

Sample:

Apo-escas13d (110 kDa, Complex from unidentified bacterium)
Apo-escas13d (Protein from unidentified bacterium)

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EMDB [3]

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