Structure of LARP7 protein p65-telomerase RNA complex in telomerase
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8gap
Q-score: 0.323
Wang Y, He Y, Wang Y, Yang Y, Singh M, Eichhorn CD, Cheng X, Jiang YX, Zhou ZH, Feigon J
J Mol Biol (2023) 435 pp. 168044-168044 [ Pubmed: 37330293 DOI: doi:10.1016/j.jmb.2023.168044 ]
- Telomerase rna (50 kDa, RNA from Tetrahymena thermophila)
- Tetrahymena telomerase holoenzyme (Complex from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)
- Telomerase holoenzyme teb1 subunit (82 kDa, Protein from Tetrahymena thermophila)
- Telomerase reverse transcriptase (133 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb3 subunit (14 kDa, Protein from Tetrahymena thermophila)
- Telomere dna (9 kDa, DNA from synthetic construct)
- Telomerase holoenzyme teb2 subunit (30 kDa, Protein from Tetrahymena thermophila)
- Telomerase la-related protein p65 (64 kDa, Protein from Tetrahymena thermophila)
- Telomerase associated protein p50 (50 kDa, Protein from Tetrahymena thermophila)
Tetrahymena telomerase with CST
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7uy5
Q-score: 0.422
He Y, Song H, Chan H, Liu B, Wang Y, Susac L, Zhou ZH, Feigon J
Nature (2022) 608 pp. 813-818 [ Pubmed: 35831498 DOI: doi:10.1038/s41586-022-04931-7 ]
- Tetrahymena telomerase holoenzyme (Complex from Tetrahymena thermophila)
- Telomerase holoenzyme teb3 subunit (14 kDa, Protein from Tetrahymena thermophila)
- Telomerase-associated protein of 19 kda (19 kDa, Protein from Tetrahymena thermophila)
- Telomerase-associated protein of 75 kda (73 kDa, Protein from Tetrahymena thermophila)
- Telomerase rna (50 kDa, RNA from Tetrahymena thermophila)
- Telomerase associated protein p50 (50 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb2 subunit (30 kDa, Protein from Tetrahymena thermophila)
- Telomerase reverse transcriptase (133 kDa, Protein from Tetrahymena thermophila)
- Telomere dna (9 kDa, DNA from Tetrahymena thermophila)
- Telomerase la-related protein p65 (64 kDa, Protein from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)
- Telomerase holoenzyme teb1 subunit (82 kDa, Protein from Tetrahymena thermophila)
- Telomerase-associated protein of 45 kda (43 kDa, Protein from Tetrahymena thermophila)
Tetrahymena telomerase at 2.9 Angstrom resolution
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7uy6
Q-score: 0.506
He Y, Song H, Chan H, Liu B, Wang Y, Susac L, Zhou ZH, Feigon J
Nature (2022) 608 pp. 813-818 [ Pubmed: 35831498 DOI: doi:10.1038/s41586-022-04931-7 ]
- Tetrahymena telomerase holoenzyme (Complex from Tetrahymena thermophila)
- Telomerase holoenzyme teb3 subunit (14 kDa, Protein from Tetrahymena thermophila)
- Telomere dna (19 kDa, DNA from Tetrahymena thermophila)
- Telomerase rna (50 kDa, RNA from Tetrahymena thermophila)
- Telomerase associated protein p50 (50 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb2 subunit (30 kDa, Protein from Tetrahymena thermophila)
- Telomerase reverse transcriptase (133 kDa, Protein from Tetrahymena thermophila)
- Telomerase la-related protein p65 (64 kDa, Protein from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)
- Telomerase holoenzyme teb1 subunit (82 kDa, Protein from Tetrahymena thermophila)
Tetrahymena CST with Polymerase alpha-Primase
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7uy7
Q-score: 0.293
He Y, Song H, Chan H, Liu B, Wang Y, Susac L, Zhou ZH, Feigon J
Nature (2022) 608 pp. 813-818 [ Pubmed: 35831498 DOI: doi:10.1038/s41586-022-04931-7 ]
- Telomere dna (19 kDa, DNA from Tetrahymena thermophila)
- Telomerase-associated protein of 19 kda (19 kDa, Protein from Tetrahymena thermophila)
- Telomerase-associated protein of 75 kda (73 kDa, Protein from Tetrahymena thermophila)
- Dna polymerase (161 kDa, Protein from Tetrahymena thermophila)
- Telomerase associated protein p50 (50 kDa, Protein from Tetrahymena thermophila)
- Tetrahymena cst (Complex from Tetrahymena thermophila)
- Tetrahymena cst-polaprim (Complex)
- Zinc ion (65 Da, Ligand)
- Tetrahymena dna polymerase alpha-primase (Complex from Tetrahymena thermophila)
- Telomerase-associated protein of 45 kda (43 kDa, Protein from Tetrahymena thermophila)
Tetrahymena Polymerase alpha-Primase
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7uy8
Q-score: 0.229
He Y, Song H, Chan H, Liu B, Wang Y, Susac L, Zhou ZH, Feigon J
Nature (2022) 608 pp. 813-818 [ Pubmed: 35831498 DOI: doi:10.1038/s41586-022-04931-7 ]
- Dna polymerase alpha subunit b (68 kDa, Protein from Tetrahymena thermophila)
- Dna polymerase (161 kDa, Protein from Tetrahymena thermophila)
- Dna primase (47 kDa, Protein from Tetrahymena thermophila)
- Tetrahymena polaprim (Complex from Tetrahymena thermophila)
- Eukaryotic-type dna primase, large subunit (64 kDa, Protein from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)
