Structure of SARS-CoV-2 (HP-GSAS-Mut7) spike in complex with TXG-0078 Fab -Conformation 1
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B
To Be Published
Structure of SARS-CoV-2 (HP-GSAS-Mut7) spike in complex with TXG-0078 Fab -Conformation 2
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B
To Be Published
Local refinement of SARS-CoV-2 (HP-GSAS-Mut7) spike NTD in complex with TXG-0078 Fab
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Txg-0078 fab light chain (14 kDa, Protein from Homo sapiens)
- Txg-0078 fab heavy chain (16 kDa, Protein from Homo sapiens)
- Structure of sars-cov-2(hp-gsas-mut7) spike in complex with txg-0078 fab- local refinement (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-2 CoV 6P Mut7 in complex with Fab CC84.5
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schafer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R
Nat Immunol (2022) 23 pp. 960-970 [ Pubmed: 35654851 DOI: doi:10.1038/s41590-022-01222-1 ]
SARS-CoV-2 6P Mut7 in complex with K398.25 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ DOI: doi:10.1126/scitranslmed.abl9605 Pubmed: 35947674 ]
SARS-CoV-1 in complex with K398.25 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ DOI: doi:10.1126/scitranslmed.abl9605 Pubmed: 35947674 ]
SARS-CoV-2 6P Mut7 in complex with K398.16 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ DOI: doi:10.1126/scitranslmed.abl9605 Pubmed: 35947674 ]
SARS-CoV-2 6P Mut7 in complex with K398.16 Fab (3 bound)
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ DOI: doi:10.1126/scitranslmed.abl9605 Pubmed: 35947674 ]
SARS-CoV-1 in complex with K398.16 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ DOI: doi:10.1126/scitranslmed.abl9605 Pubmed: 35947674 ]
SARS-CoV-2 6P Mut7 in complex with K288.2 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ DOI: doi:10.1126/scitranslmed.abl9605 Pubmed: 35947674 ]