RBD of SARS-CoV2 spike protein with ACE2 decoy
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8jje
Q-score: 0.488
Urano E, Itoh Y, Suzuki T, Sasaki T, Kishikawa JI, Akamatsu K, Higuchi Y, Sakai Y, Okamura T, Mitoma S, Sugihara F, Takada A, Kimura M, Nakao S, Hirose M, Sasaki T, Koketsu R, Tsuji S, Yanagida S, Shioda T, Hara E, Matoba S, Matsuura Y, Kanda Y, Arase H, Okada M, Takagi J, Kato T, Hoshino A, Yasutomi Y, Saito A, Okamoto T
Sci Transl Med (2023) 15 pp. eadi2623-eadi2623 [ Pubmed: 37647387 DOI: doi:10.1126/scitranslmed.adi2623 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rbd of sars-cov2 spike protein with ace2 decoy. (460 kDa, Complex)
- Sars-cov2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (138 kDa, Protein from synthetic construct)
- Water (18 Da, Ligand)
- Angiotensin-converting enzyme 2 (73 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Sulfate ion (96 Da, Ligand)
- Ace2 (Complex from Homo sapiens)
Cryo-EM structure of the histamine-bound histamine H4 receptor and Gq complex
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7yfc
Q-score: 0.539
Im D, Kishikawa JI, Shiimura Y, Hisano H, Ito A, Fujita-Fujiharu Y, Sugita Y, Noda T, Kato T, Asada H, Iwata S
Nat Commun (2023) 14 pp. 6538-6538 [ Pubmed: 37863901 DOI: doi:10.1038/s41467-023-42260-z ]
- Nb35 (14 kDa, Protein from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Lama glama)
- Nb35 (Complex from Homo sapiens)
- Scfv16 (27 kDa, Protein from Mus musculus)
- Histamine-bound histamine h4 receptor in complex with gq (190 kDa, Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (42 kDa, Protein from Homo sapiens)
- Histamine h4 receptor (62 kDa, Protein from Homo sapiens)
- Engineered g-alpha-q (Complex from Homo sapiens)
- Histamine h4 receptor (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Engineered g-alpha-q (41 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Histamine (111 Da, Ligand)
- Scfv16 (Complex from Homo sapiens)
Cryo-EM structure of the imetit-bound histamine H4 receptor and Gq complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7yfd
Q-score: 0.552
Im D, Kishikawa JI, Shiimura Y, Hisano H, Ito A, Fujita-Fujiharu Y, Sugita Y, Noda T, Kato T, Asada H, Iwata S
Nat Commun (2023) 14 pp. 6538-6538 [ Pubmed: 37863901 DOI: doi:10.1038/s41467-023-42260-z ]
- Imetit bound histamine h4 receptor in complex with gq (190 kDa, Complex from Homo sapiens)
- Nb35 (14 kDa, Protein from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Lama glama)
- Nb35 (Complex)
- Scfv16 (27 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Mus musculus)
- Histamine h4 receptor (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (42 kDa, Protein from Homo sapiens)
- Engineered g-alpha-q (Complex from Homo sapiens)
- Histamine h4 receptor (62 kDa, Protein from Homo sapiens)
- 2-(1~{h}-imidazol-5-yl)ethyl carbamimidothioate (170 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Engineered g-alpha-q (41 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Scfv16 (Complex from Homo sapiens)
Cryo-EM structure of MrgD-Gi complex with beta-alanine
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7y12
Q-score: 0.519
Suzuki S, Iida M, Hiroaki Y, Tanaka K, Kawamoto A, Kato T, Oshima A
Commun Biol (2022) 5 pp. 707-707 [ DOI: doi:10.1038/s42003-022-03668-3 Pubmed: 35840655 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Mus musculus)
- Soluble cytochrome b562,mas-related g-protein coupled receptor member d (50 kDa, Protein from Homo sapiens)
- Palmitic acid (256 Da, Ligand)
- Beta-alanine bound mrgd-gi complex with the scfv16 (Complex from Homo sapiens)
- Beta-alanine (89 Da, Ligand)
- Scfv16 (31 kDa, Protein from synthetic construct)
- G(i) subunit alpha-1,mas-related g-protein coupled receptor member d (Complex from Mus musculus)
- Subunit beta-1,subunit gamma-2 (Complex from synthetic construct)
- Scfv16 (Complex)
Cryo-EM structure of apo-state MrgD-Gi complex (local)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7y13
Q-score: 0.512
Suzuki S, Iida M, Hiroaki Y, Tanaka K, Kawamoto A, Kato T, Oshima A
Commun Biol (2022) 5 pp. 707-707 [ DOI: doi:10.1038/s42003-022-03668-3 Pubmed: 35840655 ]
- Palmitic acid (256 Da, Ligand)
- Soluble cytochrome b562,mas-related g-protein coupled receptor member d (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Soluble cytochrome b562,mas-related g-protein coupled receptor member d (50 kDa, Protein from Homo sapiens)
Cryo-EM structure of MrgD-Gi complex with beta-alanine (local)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7y14
Q-score: 0.494
Suzuki S, Iida M, Hiroaki Y, Tanaka K, Kawamoto A, Kato T, Oshima A
Commun Biol (2022) 5 pp. 707-707 [ DOI: doi:10.1038/s42003-022-03668-3 Pubmed: 35840655 ]
- Palmitic acid (256 Da, Ligand)
- Soluble cytochrome b562,mas-related g-protein coupled receptor member d (50 kDa, Protein from Homo sapiens)
- Beta-alanine bound mrgd-gi complex with the scfv16 (Complex from Homo sapiens)
- Beta-alanine (89 Da, Ligand)
Cryo-EM structure of apo-state MrgD-Gi complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7y15
Q-score: 0.552
Suzuki S, Iida M, Hiroaki Y, Tanaka K, Kawamoto A, Kato T, Oshima A
Commun Biol (2022) 5 pp. 707-707 [ DOI: doi:10.1038/s42003-022-03668-3 Pubmed: 35840655 ]
- Mrgd-gi complex with the scfv16 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Mus musculus)
- Soluble cytochrome b562,mas-related g-protein coupled receptor member d (50 kDa, Protein from Homo sapiens)
- Palmitic acid (256 Da, Ligand)
- Scfv16 (31 kDa, Protein from synthetic construct)
- G(i) subunit alpha-1,mas-related g-protein coupled receptor member d (Complex from Mus musculus)
- Subunit beta-1,subunit gamma-2 (Complex from synthetic construct)
- Scfv16 (Complex)