Do data resources managed by EMBL-EBI and our collaborators make a difference to your work? Please take 10 minutes to fill in our annual user survey, and help us make the case for why sustaining open data resources is critical for life sciences research. We appreciate your responses prior to closing of the survey on Monday 17th June.
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7uol
Q-score: 0.52
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7uom
Q-score: 0.457
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8dql
Q-score: 0.54
Liu X, Clemens DL, Lee BY, Yang X, Zhou ZH, Horwitz MA
Mbio (2022) 13 pp. e0127722-e0127722 [ Pubmed: 36036641 DOI: doi:10.1128/mbio.01277-22 ]
Tetrahymena telomerase with CST
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7uy5
Q-score: 0.422
He Y, Song H, Chan H, Liu B, Wang Y, Susac L, Zhou ZH, Feigon J
Nature (2022) 608 pp. 813-818 [ DOI: doi:10.1038/s41586-022-04931-7 Pubmed: 35831498 ]
- Telomerase-associated protein of 19 kda (19 kDa, Protein from Tetrahymena thermophila)
- Telomerase rna (50 kDa, RNA from Tetrahymena thermophila)
- Telomerase holoenzyme teb1 subunit (82 kDa, Protein from Tetrahymena thermophila)
- Tetrahymena telomerase holoenzyme (Complex from Tetrahymena thermophila)
- Telomerase reverse transcriptase (133 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb3 subunit (14 kDa, Protein from Tetrahymena thermophila)
- Telomerase associated protein p50 (50 kDa, Protein from Tetrahymena thermophila)
- Telomerase-associated protein of 75 kda (73 kDa, Protein from Tetrahymena thermophila)
- Telomerase la-related protein p65 (64 kDa, Protein from Tetrahymena thermophila)
- Telomerase-associated protein of 45 kda (43 kDa, Protein from Tetrahymena thermophila)
- Telomere dna (9 kDa, DNA from Tetrahymena thermophila)
- Telomerase holoenzyme teb2 subunit (30 kDa, Protein from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)
Tetrahymena telomerase at 2.9 Angstrom resolution
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7uy6
Q-score: 0.506
He Y, Song H, Chan H, Liu B, Wang Y, Susac L, Zhou ZH, Feigon J
Nature (2022) 608 pp. 813-818 [ DOI: doi:10.1038/s41586-022-04931-7 Pubmed: 35831498 ]
- Telomerase rna (50 kDa, RNA from Tetrahymena thermophila)
- Telomerase holoenzyme teb1 subunit (82 kDa, Protein from Tetrahymena thermophila)
- Tetrahymena telomerase holoenzyme (Complex from Tetrahymena thermophila)
- Telomere dna (19 kDa, DNA from Tetrahymena thermophila)
- Telomerase reverse transcriptase (133 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb3 subunit (14 kDa, Protein from Tetrahymena thermophila)
- Telomerase associated protein p50 (50 kDa, Protein from Tetrahymena thermophila)
- Telomerase la-related protein p65 (64 kDa, Protein from Tetrahymena thermophila)
- Telomerase holoenzyme teb2 subunit (30 kDa, Protein from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)
Tetrahymena CST with Polymerase alpha-Primase
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7uy7
Q-score: 0.293
He Y, Song H, Chan H, Liu B, Wang Y, Susac L, Zhou ZH, Feigon J
Nature (2022) 608 pp. 813-818 [ DOI: doi:10.1038/s41586-022-04931-7 Pubmed: 35831498 ]
- Telomerase-associated protein of 19 kda (19 kDa, Protein from Tetrahymena thermophila)
- Tetrahymena cst-polaprim (Complex)
- Telomere dna (19 kDa, DNA from Tetrahymena thermophila)
- Telomerase-associated protein of 75 kda (73 kDa, Protein from Tetrahymena thermophila)
- Tetrahymena dna polymerase alpha-primase (Complex from Tetrahymena thermophila)
- Telomerase-associated protein of 45 kda (43 kDa, Protein from Tetrahymena thermophila)
- Dna polymerase (161 kDa, Protein from Tetrahymena thermophila)
- Telomerase associated protein p50 (50 kDa, Protein from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)
- Tetrahymena cst (Complex from Tetrahymena thermophila)
Tetrahymena Polymerase alpha-Primase
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7uy8
Q-score: 0.229
He Y, Song H, Chan H, Liu B, Wang Y, Susac L, Zhou ZH, Feigon J
Nature (2022) 608 pp. 813-818 [ DOI: doi:10.1038/s41586-022-04931-7 Pubmed: 35831498 ]
- Dna polymerase alpha subunit b (68 kDa, Protein from Tetrahymena thermophila)
- Dna primase (47 kDa, Protein from Tetrahymena thermophila)
- Eukaryotic-type dna primase, large subunit (64 kDa, Protein from Tetrahymena thermophila)
- Tetrahymena polaprim (Complex from Tetrahymena thermophila)
- Dna polymerase (161 kDa, Protein from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)