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Resolution: 2.33 Å
EM Method: Single-particle
Fitted PDBs: 8ud2
Q-score: 0.672
SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, consensus form
Resolution: 2.67 Å
EM Method: Single-particle
Fitted PDBs: 8ud3
Q-score: 0.605
Ito F, Yang H, Zhou ZH, Chen XS
Protein Cell (2024) [ Pubmed: 38613382 DOI: doi:10.1093/procel/pwae009 ]
- Rna (35-mer) (11 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Rna (35-mer) (10 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 15 (40 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Homohexamer of nsp15 in complex with poly(a/u) rna (262 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 1
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8ud4
Q-score: 0.511
Ito F, Yang H, Zhou ZH, Chen XS
Protein Cell (2024) [ Pubmed: 38613382 DOI: doi:10.1093/procel/pwae009 ]
- Rna (35-mer) (11 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Rna (35-mer) (10 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 15 (40 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Homohexamer of nsp15 in complex with rna duplex (262 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 2
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8ud5
Q-score: 0.541
Ito F, Yang H, Zhou ZH, Chen XS
Protein Cell (2024) [ Pubmed: 38613382 DOI: doi:10.1093/procel/pwae009 ]
- Rna (35-mer) (11 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Rna (35-mer) (10 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 15 (40 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Homohexamer of nsp15 in complex with rna duplex (262 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
Full-length APOBEC3G in complex with HIV-1 Vif, CBF-beta, and fork RNA
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 8e40
Q-score: 0.343
Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS
Sci Adv (2023) 9 pp. eade3168-eade3168 [ Pubmed: 36598981 DOI: doi:10.1126/sciadv.ade3168 ]
- Rna (8 kDa, RNA from Escherichia coli)
- Virion infectivity factor (21 kDa, Protein from Human immunodeficiency virus 1)
- Rna (6 kDa, RNA from Escherichia coli)
- Complex of apobec3g with hiv-1 vif and cbf-beta bound to fork rna (99 kDa, Complex from Human immunodeficiency virus 1)
- Core-binding factor subunit beta (18 kDa, Protein from Homo sapiens)
- Dna dc->du-editing enzyme apobec-3g (45 kDa, Protein from Macaca mulatta)
- Zinc ion (65 Da, Ligand)
APOBEC3G in complex with HIV-1 Vif/CBF-beta/EloB/EloC/Cul5/Rbx2
Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS
Sci Adv (2023) 9 pp. eade3168-eade3168 [ Pubmed: 36598981 DOI: doi:10.1126/sciadv.ade3168 ]
- Elongin-c (Protein from Homo sapiens)
- Cullin-5 (Protein from Homo sapiens)
- Apobec3g (Protein from Macaca mulatta)
- Virion infectivity factor (Protein from Human immunodeficiency virus 1)
- Ring-box protein 2 (Protein from Homo sapiens)
- Complex of apobec3g with hiv-1 vif, cbf-beta, elongin-b, elongin-c, cullin-5, and ring-box protein 2 (210 kDa, Complex from Human immunodeficiency virus 1)
- Elongin-b (Protein from Homo sapiens)
- Core-binding factor subunit beta (Protein from Homo sapiens)
Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS
Sci Adv (2023) 9 pp. eade3168-eade3168 [ Pubmed: 36598981 DOI: doi:10.1126/sciadv.ade3168 ]
- Apobec3g (Protein from Macaca mulatta)
- Apobec3g dimer mediated by rna (108 kDa, Complex from Macaca mulatta)