Structure of Machupo virus L polymerase in complex with Z protein and 3'-vRNA (dimeric complex)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7el9
Q-score: 0.415
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ Pubmed: 34127846 DOI: doi:10.1038/s41564-021-00916-w ]
- Machupo virus polymerase (Complex)
- Machupo virus 3'-vrna promoter (Complex from Machupo mammarenavirus)
- Manganese (ii) ion (54 Da, Ligand)
- Machupo virus z matrix protein (Complex)
- Rna-directed rna polymerase l (250 kDa, Protein from Machupo mammarenavirus)
- Machupo virus 3'-vrna promoter (6 kDa, RNA from Machupo mammarenavirus)
- Ring finger protein z (10 kDa, Protein from Machupo mammarenavirus)
- Machupo virus polymerase in complex with z martix protein and 3'-vrna in dimeric form. (580 kDa, Complex from Machupo mammarenavirus)
- Zinc ion (65 Da, Ligand)
Structure of Machupo virus L polymerase in complex with Z protein (dimeric form)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7elb
Q-score: 0.229
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ Pubmed: 34127846 DOI: doi:10.1038/s41564-021-00916-w ]
- Manganese (ii) ion (54 Da, Ligand)
- Rna-directed rna polymerase l (250 kDa, Protein from Machupo mammarenavirus)
- Machupo virus z matrix protein (Complex)
- Ring finger protein z (10 kDa, Protein from Machupo mammarenavirus)
- Machupo virus polymerase in complex with z protein (dimeric form). (580 kDa, Complex from Machupo mammarenavirus)
- Machupo virus polymerase (Complex from Machupo mammarenavirus)
- Zinc ion (65 Da, Ligand)
Intact human mitochondrial calcium uniporter complex with MICU1/MICU2 subunits
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6k7y
Q-score: 0.511
Zhuo W, Zhou H, Guo R, Yi J, Zhang L, Yu L, Sui Y, Zeng W, Wang P, Yang M
Protein Cell (2021) 12 pp. 220-229 [ DOI: doi:10.1007/s13238-020-00776-w Pubmed: 32862359 ]
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Calcium uptake protein 2, mitochondrial (39 kDa, Protein from Homo sapiens)
- Essential mcu regulator, mitochondrial (5 kDa, Protein from Homo sapiens)
- Calcium uniporter protein, mitochondrial (32 kDa, Protein from Homo sapiens)
- Calcium uptake protein 1, mitochondrial (54 kDa, Protein from Homo sapiens)
- Cardiolipin (1 kDa, Ligand)
- Calcium ion (40 Da, Ligand)
- Intact human mitochondrial calcium uniporter complex with micu1/micu2 subunits (Complex from Homo sapiens)
Dimeric structure of Machupo virus polymerase bound to vRNA promoter
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6klh
Q-score: 0.321
Peng R, Xu X, Jing J, Wang M, Peng Q, Liu S, Wu Y, Bao X, Wang P, Qi J, Gao GF, Shi Y
Nature (2020) 579 pp. 615-619 [ Pubmed: 32214249 DOI: doi:10.1038/s41586-020-2114-2 ]
- Manganese (ii) ion (54 Da, Ligand)
- Rna-directed rna polymerase l (250 kDa, Protein from Machupo virus)
- Zinc ion (65 Da, Ligand)
- Machupo virus polymerase bound to vrna promoter (540 kDa, Complex from Machupo mammarenavirus)
- Rna (5'-r(*gp*cp*cp*up*ap*gp*gp*ap*up*cp*cp*ap*cp*up*gp*up*gp*cp*g)-3') (6 kDa, RNA from synthetic construct)