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Liu B, Liu H, Han P, Wang X, Wang C, Yan X, Lei W, Xu K, Zhou J, Qi J, Fan R, Wu G, Tian WX, Gao GF, Wang Q
Signal Transduct Target Ther (2024) 9 pp. 131-131 [ Pubmed: 38740785 DOI: doi:10.1038/s41392-024-01847-8 ]
- S2l20 heavy chain (52 kDa, Protein from Homo sapiens)
- Nanobody n235 (13 kDa, Protein from Vicugna pacos)
- The n-terminal domain of omicron ba.1 in complex with nanobody n235 and s2l20 fab (Complex from Vicugna pacos)
- Spike protein s2' (34 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S2l20 light chain (26 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with hippopotamus ACE2
Resolution: 2.62 Å
EM Method: Single-particle
Fitted PDBs: 8wlo
Q-score: 0.429
Yang R, Han P, Han P, Li D, Zhao R, Niu S, Liu K, Li S, Tian WX, Gao GF
J Virol (2024) 98 pp. e0045124-e0045124 [ Pubmed: 38591877 DOI: doi:10.1128/jvi.00451-24 ]
- Angiotensin-converting enzyme (69 kDa, Protein from Hippopotamus amphibius)
- Spike glycoprotein (135 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 prototype spike protein in complex with hippopotamus ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 8wlr
Q-score: 0.553
Yang R, Han P, Han P, Li D, Zhao R, Niu S, Liu K, Li S, Tian WX, Gao GF
J Virol (2024) 98 pp. e0045124-e0045124 [ Pubmed: 38591877 DOI: doi:10.1128/jvi.00451-24 ]
- Angiotensin-converting enzyme (69 kDa, Protein from Hippopotamus amphibius)
- Spike glycoprotein (135 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Sars-cov-2 prototype spike protein receptor-binding domain in complex with hippopotamus ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 S-trimer in complex with fab L4.65 and L5.34
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 8hp9
Q-score: 0.368
Guo S, Zheng Y, Gao Z, Duan M, Liu S, Du P, Xu X, Xu K, Zhao X, Chai Y, Wang P, Zhao Q, Gao GF, Dai L
Cell Discov (2023) 9 pp. 79-79 [ Pubmed: 37507370 DOI: doi:10.1038/s41421-023-00585-5 ]
- Fab l5.34 (23 kDa, Protein from Homo sapiens)
- Spike protein s2' (125 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 omicron ba.2 s-trimer in complex with fab l4.65 and l5.34 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab l4.65 (23 kDa, Protein from Homo sapiens)
- Fab l5.34 (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab l4.65 (24 kDa, Protein from Homo sapiens)
Cryo-EM structure of SARS-CoV-2 Omicron BA.4 S-trimer in complex with fab L4.65 and L5.34
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8hpq
Q-score: 0.243
Guo S, Zheng Y, Gao Z, Duan M, Liu S, Du P, Xu X, Xu K, Zhao X, Chai Y, Wang P, Zhao Q, Gao GF, Dai L
Cell Discov (2023) 9 pp. 79-79 [ Pubmed: 37507370 DOI: doi:10.1038/s41421-023-00585-5 ]
- Spike protein s2' (125 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab l5.34 (23 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 omicron ba.4 s-trimer in complex with fab l4.65 and l5.34 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab l4.65 (23 kDa, Protein from Homo sapiens)
- Fab l5.34 (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab l4.65 (24 kDa, Protein from Homo sapiens)
Cryo-EM structure of SARS-CoV-2 Omicron Prototype S-trimer in complex with fab L4.65 and L5.34
Resolution: 2.65 Å
EM Method: Single-particle
Fitted PDBs: 8hpv
Q-score: 0.34
Guo S, Zheng Y, Gao Z, Duan M, Liu S, Du P, Xu X, Xu K, Zhao X, Chai Y, Wang P, Zhao Q, Gao GF, Dai L
Cell Discov (2023) 9 pp. 79-79 [ Pubmed: 37507370 DOI: doi:10.1038/s41421-023-00585-5 ]
- Spike protein s2' (125 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab l5.34 (23 kDa, Protein from Homo sapiens)
- Fab l5.34 (23 kDa, Protein from Homo sapiens)
- Fab l4.65 (23 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 omicron prototype s-trimer in complex with fab l4.65 and l5.34 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab l4.65 (24 kDa, Protein from Homo sapiens)
Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with golden hamster ACE2 (local refinement)
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8ka8
Q-score: 0.486
Niu S, Zhao Z, Liu Z, Rong X, Chai Y, Bai B, Han P, Shang G, Ren J, Wang Y, Zhao X, Liu K, Tian WX, Wang Q, Gao GF
J Virol (2024) 98 pp. e0115723-e0115723 [ DOI: doi:10.1128/jvi.01157-23 Pubmed: 38305152 ]
- Golden hamster angiotensin-converting enzyme 2 (Complex from Mesocricetus auratus)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Delta rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme (68 kDa, Protein from Mesocricetus auratus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of sars-cov-2 delta rbd in complex with golden hamster ace2 (local refinement) (Complex)
Cryo-EM structure of SARS-CoV-2 BA.3 RBD in complex with golden hamster ACE2 (local refinement)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8kc2
Q-score: 0.556
Niu S, Zhao Z, Liu Z, Rong X, Chai Y, Bai B, Han P, Shang G, Ren J, Wang Y, Zhao X, Liu K, Tian WX, Wang Q, Gao GF
J Virol (2024) 98 pp. e0115723-e0115723 [ DOI: doi:10.1128/jvi.01157-23 Pubmed: 38305152 ]
- Golden hamster angiotensin-converting enzyme 2 (Complex from Mesocricetus auratus)
- Cryo-em structure of sars-cov-2 ba.3 rbd in complex with golden hamster ace2 (local refinement) (Complex)
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme (68 kDa, Protein from Mesocricetus auratus)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Ba.3 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8xb8
Q-score: 0.49
Li C, Jia M, Hao T, Peng Q, Peng R, Chai Y, Shi Y, Song H, Gao GF
J Virol (2024) 98 pp. e0153623-e0153623 [ DOI: doi:10.1128/jvi.01536-23 Pubmed: 38315014 ]
- A137r (16 kDa, Protein from African swine fever virus)
- The structure of asfv a137r (Complex from African swine fever virus)
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with fab L4.65 and L5.34
Resolution: 2.34 Å
EM Method: Single-particle
Fitted PDBs: 8hpf
Q-score: 0.494
Guo S, Zheng Y, Gao Z, Duan M, Liu S, Du P, Xu X, Xu K, Zhao X, Chai Y, Wang P, Zhao Q, Gao GF, Dai L
Cell Discov (2023) 9 pp. 79-79 [ Pubmed: 37507370 DOI: doi:10.1038/s41421-023-00585-5 ]
- Spike protein s2' (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 omicron ba.2 rbd in complex with fab l4.65 and l5.34 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab l5.34 (23 kDa, Protein from Homo sapiens)
- Fab l4.65 (23 kDa, Protein from Homo sapiens)
- Fab l5.34 (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab l4.65 (24 kDa, Protein from Homo sapiens)