Dimer structure of yeast THO complex
Chen C, Tan M, Wu Z, Zhang Y, He F, Lu Y, Li S, Cao M, Li G, Wu J, Cheng H, Lei M
Sci Bull (Beijing) (2021) 66 pp. 2347-2352 [ Pubmed: 36654119 DOI: doi:10.1016/j.scib.2021.08.004 ]
- Thp2p (Protein from Saccharomyces cerevisiae)
- Tex1p (Protein from Saccharomyces cerevisiae)
- Mft1p (Protein from Saccharomyces cerevisiae)
- Tho complex (Complex from Saccharomyces cerevisiae S288C)
- Hpr1p (Protein from Saccharomyces cerevisiae)
- Tho2p (Protein from Saccharomyces cerevisiae)
protomer structure from the dimer of yeast THO complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7v2w
Q-score: 0.479
Chen C, Tan M, Wu Z, Zhang Y, He F, Lu Y, Li S, Cao M, Li G, Wu J, Cheng H, Lei M
Sci Bull (Beijing) (2021) 66 pp. 2347-2352 [ Pubmed: 36654119 DOI: doi:10.1016/j.scib.2021.08.004 ]
- Tho complex (Complex from Saccharomyces cerevisiae S288c)
- Tho complex subunit mft1 (45 kDa, Protein from Saccharomyces cerevisiae S288c)
- Tho complex subunit thp2 (30 kDa, Protein from Saccharomyces cerevisiae S288c)
- Tho complex subunit hpr1 (87 kDa, Protein from Saccharomyces cerevisiae S288c)
- Protein tex1 (47 kDa, Protein from Saccharomyces cerevisiae S288c)
- Tho complex subunit 2 (184 kDa, Protein from Saccharomyces cerevisiae S288c)
cryo-EM structure of yeast THO complex with Sub2
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7v2y
Q-score: 0.431
Chen C, Tan M, Wu Z, Zhang Y, He F, Lu Y, Li S, Cao M, Li G, Wu J, Cheng H, Lei M
Sci Bull (Beijing) (2021) 66 pp. 2347-2352 [ Pubmed: 36654119 DOI: doi:10.1016/j.scib.2021.08.004 ]
- Atp-dependent rna helicase sub2 (50 kDa, Protein from Saccharomyces cerevisiae S288c)
- Tho complex subunit mft1 (45 kDa, Protein from Saccharomyces cerevisiae S288c)
- Tho complex subunit thp2 (30 kDa, Protein from Saccharomyces cerevisiae S288c)
- Tho complex subunit hpr1 (87 kDa, Protein from Saccharomyces cerevisiae S288c)
- Protein tex1 (47 kDa, Protein from Saccharomyces cerevisiae S288c)
- Tho-sub2 complex (Complex from Saccharomyces cerevisiae S288c)
- Tho complex subunit 2 (184 kDa, Protein from Saccharomyces cerevisiae S288c)
- Sub2 (Complex)
- Yeast tho (Complex from Saccharomyces cerevisiae S288c)
cryo-EM structure of human RNA polymerase III in elongating state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7d58
Q-score: 0.014
Wang Q, Li S, Wan F, Xu Y, Wu Z, Cao M, Lan P, Lei M, Wu J
Nat Struct Mol Biol (2021) 28 pp. 220-227 [ DOI: doi:10.1038/s41594-021-00557-x Pubmed: 33558766 ]
- Template dna (12 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Non-template dna (12 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Rna (6 kDa, RNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc4 (44 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
- Human pol3 ec (Complex from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)
cryo-EM structure of human RNA polymerase III in apo state
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7d59
Q-score: 0.391
Wang Q, Li S, Wan F, Xu Y, Wu Z, Cao M, Lan P, Lei M, Wu J
Nat Struct Mol Biol (2021) 28 pp. 220-227 [ DOI: doi:10.1038/s41594-021-00557-x Pubmed: 33558766 ]
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)
- Rna pol3 apo (Complex from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc4 (44 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)