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Amyloid beta 42 type 2 filaments from the brainstem of individual 4
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ Pubmed: 38057661 DOI: doi:10.1038/s41586-023-06801-2 ]
TAF15 filaments from brainstem - Individual 4
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ Pubmed: 38057661 DOI: doi:10.1038/s41586-023-06801-2 ]
TAF15 filament - individual 1, motor cortex
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ Pubmed: 38057661 DOI: doi:10.1038/s41586-023-06801-2 ]
singlet TMEM type 1 filament - Individual 4, prefrontal cortex
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ Pubmed: 38057661 DOI: doi:10.1038/s41586-023-06801-2 ]
doublet TMEM type 1 filament - individual 4, brainstem
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ Pubmed: 38057661 DOI: doi:10.1038/s41586-023-06801-2 ]
doublet TMEM106B type 1 filament - individual 4, prefrontal cortex
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ Pubmed: 38057661 DOI: doi:10.1038/s41586-023-06801-2 ]
singlet TMEM type 1 filament - individual 4, brainstem
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ Pubmed: 38057661 DOI: doi:10.1038/s41586-023-06801-2 ]
TAF15 amyloid fold in atypical FTLD - Individual 1
Resolution: 1.97 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ons
Q-score: 0.749
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ Pubmed: 38057661 DOI: doi:10.1038/s41586-023-06801-2 ]
- Water (18 Da, Ligand)
- Taf15 atypical ftld amyloid fold (Tissue from Homo sapiens)
- Tata-binding protein-associated factor 2n (61 kDa, Protein from Homo sapiens)