Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6fvw
Q-score: 0.204
Eisele MR, Reed RG, Rudack T, Schweitzer A, Beck F, Nagy I, Pfeifer G, Plitzko JM, Baumeister W, Tomko Jr RJ, Sakata E
Cell Rep (2018) 24 pp. 1301-1315.e5 [ Pubmed: 30067984 DOI: doi:10.1016/j.celrep.2018.07.004 ]
- Proteasome subunit beta type-5 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn13 (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 4 homolog (43 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn8 (34 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-3 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-4 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 26s proteasome regulatory subunit rpn12 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn1 (106 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn5 (51 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn7 (46 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome subunit rpt4 (43 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-2 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 8 homolog (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome complex subunit sem1 (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn3 (55 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-2 (24 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-7 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-5 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-1 (21 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-triphosphate (507 Da, Ligand)
- 26s proteasome regulatory subunit rpn9 (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 6b homolog (43 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Probable proteasome subunit alpha type-7 (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-4 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn6 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn2 (101 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 6a (46 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 7 homolog (47 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-3 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ubiquitin carboxyl-terminal hydrolase rpn11 (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn10 (21 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-6 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-6 (24 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-1 (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Resolution: 5.4 Å
EM Method: Single-particle
Fitted PDBs: 6fvv
Q-score: 0.149
Eisele MR, Reed RG, Rudack T, Schweitzer A, Beck F, Nagy I, Pfeifer G, Plitzko JM, Baumeister W, Tomko Jr RJ, Sakata E
Cell Rep (2018) 24 pp. 1301-1315.e5 [ Pubmed: 30067984 DOI: doi:10.1016/j.celrep.2018.07.004 ]
- Proteasome subunit beta type-5 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn13 (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 4 homolog (43 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Probable proteasome subunit alpha type-7 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn8 (34 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 26s proteasome regulatory subunit rpn12 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn1 (106 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn5 (51 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-6 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn7 (46 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome subunit rpt4 (43 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome complex subunit sem1 (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn3 (55 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-2 (24 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-7 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-1 (21 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-4 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 7 homolog (46 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 6b homolog (44 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-triphosphate (507 Da, Ligand)
- 26s proteasome regulatory subunit rpn9 (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 8 homolog (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-5 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- Proteasome subunit beta type-4 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn6 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn2 (101 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 6a (46 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-3 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ubiquitin carboxyl-terminal hydrolase rpn11 (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn10 (21 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-6 (24 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-3 (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-1 (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-2 (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 6fvx
Q-score: 0.187
Eisele MR, Reed RG, Rudack T, Schweitzer A, Beck F, Nagy I, Pfeifer G, Plitzko JM, Baumeister W, Tomko Jr RJ, Sakata E
Cell Rep (2018) 24 pp. 1301-1315.e5 [ Pubmed: 30067984 DOI: doi:10.1016/j.celrep.2018.07.004 ]
- Proteasome subunit beta type-5 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Probable proteasome subunit alpha type-7 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn13 (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 4 homolog (43 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn8 (34 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-2 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-3 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-4 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 26s proteasome regulatory subunit rpn12 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn1 (106 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn5 (51 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn7 (46 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome subunit rpt4 (43 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome complex subunit sem1 (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn3 (55 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-2 (24 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-7 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-1 (21 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 6b homolog (44 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-triphosphate (507 Da, Ligand)
- 26s proteasome regulatory subunit rpn9 (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 8 homolog (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-5 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- Proteasome subunit beta type-4 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-1 (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn2 (101 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn6 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 6a (46 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 7 homolog (47 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-3 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ubiquitin carboxyl-terminal hydrolase rpn11 (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn10 (21 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-6 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-6 (24 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Resolution: 6.1 Å
EM Method: Single-particle
Fitted PDBs: 6fvy
Q-score: 0.136
Eisele MR, Reed RG, Rudack T, Schweitzer A, Beck F, Nagy I, Pfeifer G, Plitzko JM, Baumeister W, Tomko Jr RJ, Sakata E
Cell Rep (2018) 24 pp. 1301-1315.e5 [ Pubmed: 30067984 DOI: doi:10.1016/j.celrep.2018.07.004 ]
- Proteasome subunit beta type-5 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn13 (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 4 homolog (43 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn8 (34 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-3 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-4 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 26s proteasome regulatory subunit rpn12 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn1 (106 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn5 (51 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn7 (46 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome subunit rpt4 (43 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome complex subunit sem1 (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn3 (55 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-2 (24 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-7 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-5 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-1 (21 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 6b homolog (44 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-triphosphate (507 Da, Ligand)
- 26s proteasome regulatory subunit rpn9 (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-2 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 8 homolog (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- Probable proteasome subunit alpha type-7 (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-4 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn6 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn2 (101 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 6a (46 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit 7 homolog (47 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-3 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ubiquitin carboxyl-terminal hydrolase rpn11 (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn10 (21 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-6 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-6 (24 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-1 (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
The human 26S Proteasome at 6.8 Ang.
Resolution: 6.8 Å
EM Method: Single-particle
Fitted PDBs: 5ln3
Q-score: 0.141
Wang X, Cimermancic P, Yu C, Schweitzer A, Chopra N, Engel JL, Greenberg C, Huszagh AS, Beck F, Sakata E, Yang Y, Novitsky EJ, Leitner A, Nanni P, Kahraman A, Guo X, Dixon JE, Rychnovsky SD, Aebersold R, Baumeister W, Sali A, Huang L
Mol Cell Proteomics (2017) 16 pp. 840-854 [ Pubmed: 28292943 DOI: doi:10.1074/mcp.M116.065326 ]
- 26s protease regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 8 (45 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 10b (44 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- 26s proteasome complex subunit dss1 (8 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
- Human 26s proteasome (2 MDa, Complex from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 3 (61 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 6b (47 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (30 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-1 (29 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
26S proteasome in presence of ATP (s1)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 5mp9, 5mpd
Q-score: 0.2815
Wehmer M, Rudack T, Beck F, Aufderheide A, Pfeifer G, Plitzko JM, Forster F, Schulten K, Baumeister W, Sakata E
PNAS (2017) 114 pp. 1305-1310 [ Pubmed: 28115689 DOI: doi:10.1073/pnas.1621129114 ]
- 26s proteasome of saccharomyces cerevisiae in presence of atp (s1) (1 MDa, Complex from Saccharomyces cerevisiae S288c)
- Proteasome subunit alpha type-2 (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 6b homolog (47 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-5 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Proteasome subunit alpha type-4 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-1 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-1 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-5 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 8 homolog (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 7 homolog (52 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-6 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 6a (48 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-4 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-3 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-2 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-6 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- 26s protease regulatory subunit 4 homolog (48 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Probable proteasome subunit alpha type-7 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease subunit rpt4 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-7 (29 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
26S proteasome in presence of ATP (s2)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 5mpa, 5mpe
Q-score: 0.2305
Wehmer M, Rudack T, Beck F, Aufderheide A, Pfeifer G, Plitzko JM, Forster F, Schulten K, Baumeister W, Sakata E
PNAS (2017) 114 pp. 1305-1310 [ Pubmed: 28115689 DOI: doi:10.1073/pnas.1621129114 ]
- 26s proteasome of saccharomyces cerevisiae in presence of atp (s2) (1 MDa, Complex from Saccharomyces cerevisiae S288c)
- Proteasome subunit alpha type-2 (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 6b homolog (47 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-5 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Proteasome subunit alpha type-4 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-1 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-1 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-5 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 8 homolog (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 7 homolog (52 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-6 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 6a (48 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-4 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-3 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-2 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-6 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- 26s protease regulatory subunit 4 homolog (48 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Probable proteasome subunit alpha type-7 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease subunit rpt4 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-7 (29 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
26S proteasome in presence of AMP-PNP (s3)
Resolution: 7.8 Å
EM Method: Single-particle
Fitted PDBs: 5mpb
Q-score: 0.132
Wehmer M, Rudack T, Beck F, Aufderheide A, Pfeifer G, Plitzko JM, Forster F, Schulten K, Baumeister W, Sakata E
PNAS (2017) 114 pp. 1305-1310 [ Pubmed: 28115689 DOI: doi:10.1073/pnas.1621129114 ]
- Proteasome subunit alpha type-2 (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn1 (109 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 6b homolog (47 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-5 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 26s proteasome regulatory subunit rpn2 (104 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn8 (38 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-4 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn12 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-1 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-1 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-5 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome complex subunit sem1 (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 8 homolog (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 7 homolog (52 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-6 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 6a (48 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- 26s proteasome regulatory subunit rpn7 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-3 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-4 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-3 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-2 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-6 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn10 (29 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn13 (17 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- 26s proteasome regulatory subunit rpn6 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn9 (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn5 (51 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome of saccharomyces cerevisiae in presence of amp-pnp (1 MDa, Complex from Saccharomyces cerevisiae S288c)
- Ubiquitin carboxyl-terminal hydrolase rpn11 (34 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 4 homolog (48 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn3 (60 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Probable proteasome subunit alpha type-7 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease subunit rpt4 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-7 (29 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
26S proteasome in presence of BeFx (s4)
Resolution: 7.7 Å
EM Method: Single-particle
Fitted PDBs: 5mpc
Q-score: 0.135
Wehmer M, Rudack T, Beck F, Aufderheide A, Pfeifer G, Plitzko JM, Forster F, Schulten K, Baumeister W, Sakata E
PNAS (2017) 114 pp. 1305-1310 [ Pubmed: 28115689 DOI: doi:10.1073/pnas.1621129114 ]
- 26s proteasome of saccharomyces cerevisiae in presence of befx (s4) (1 MDa, Complex from Saccharomyces cerevisiae S288c)
- Proteasome subunit alpha type-2 (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn1 (109 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 6b homolog (47 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-5 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 26s proteasome regulatory subunit rpn2 (104 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn8 (38 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-4 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn12 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-1 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-1 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-5 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome complex subunit sem1 (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 8 homolog (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 7 homolog (52 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-6 (26 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 6a (48 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn7 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-4 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-3 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-2 (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit alpha type-6 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn10 (29 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn13 (17 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ubiquitin carboxyl-terminal hydrolase 6 (57 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- 26s proteasome regulatory subunit rpn6 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn9 (45 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn5 (51 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ubiquitin carboxyl-terminal hydrolase rpn11 (34 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease regulatory subunit 4 homolog (48 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s proteasome regulatory subunit rpn3 (60 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Probable proteasome subunit alpha type-7 (31 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 26s protease subunit rpt4 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Proteasome subunit beta type-7 (29 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
The human 26S proteasome at 3.9
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 5l4g, 5l4k
Q-score: 0.329
Schweitzer A, Aufderheide A, Rudack T, Beck F, Pfeifer G, Plitzko JM, Sakata E, Schulten K, Forster F, Baumeister W
PNAS (2016) 113 pp. 7816-7821 [ DOI: doi:10.1073/pnas.1608050113 Pubmed: 27342858 ]
- Human 26s proteasome (2 MDa, Complex from Homo sapiens)