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SARS-CoV-2 Frameshift Stimulatory Element with Upstream Multibranch Loop
Peterson JM, Becker ST, O'Leary CA, Juneja P, Yang Y, Moss WN
Biochemistry (2024) 63 pp. 1287-1296 [ DOI: doi:10.1021/acs.biochem.3c00716 Pubmed: 38727003 ]
Cryo-EM structure of SARS-CoV-2 prototype-Beta chimeric RBD-dimer bound to CB6 Fab
Xu K, Gao P, Liu S, Lu S, Lei W, Zheng T, Liu X, Xie Y, Zhao Z, Guo S, Tang C, Yang Y, Yu W, Wang J, Zhou Y, Huang Q, Liu C, An Y, Zhang R, Han Y, Duan M, Wang S, Yang C, Wu C, Liu X, She G, Liu Y, Zhao X, Xu K, Qi J, Wu G, Peng X, Dai L, Wang P, Gao GF
Cell (2022) 185 pp. 2265- [ DOI: doi:10.1016/j.cell.2022.04.029 ]
Cryo-EM structure of SARS-CoV-2 Delta-Omicron chimeric RBD-dimer bound to CB6 Fab
Xu K, Gao P, Liu S, Lu S, Lei W, Zheng T, Liu X, Xie Y, Zhao Z, Guo S, Tang C, Yang Y, Yu W, Wang J, Zhou Y, Huang Q, Liu C, An Y, Zhang R, Han Y, Duan M, Wang S, Yang C, Wu C, Liu X, She G, Liu Y, Zhao X, Xu K, Qi J, Wu G, Peng X, Dai L, Wang P, Gao GF
Cell (2022) 185 pp. 2265- [ DOI: doi:10.1016/j.cell.2022.04.029 ]
Cryo-EM structure of SARS-CoV-2 prototype RBD-dimer bound to CB6 Fab
Xu K, Gao P, Liu S, Lu S, Lei W, Zheng T, Liu X, Xie Y, Zhao Z, Guo S, Tang C, Yang Y, Yu W, Wang J, Zhou Y, Huang Q, Liu C, An Y, Zhang R, Han Y, Duan M, Wang S, Yang C, Wu C, Liu X, She G, Liu Y, Zhao X, Xu K, Qi J, Wu G, Peng X, Dai L, Wang P, Gao GF
Cell (2022) 185 pp. 2265-2278.e14 [ Pubmed: 35568034 DOI: doi:10.1016/j.cell.2022.04.029 ]
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 1 conformation
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8heb
Q-score: 0.379
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ Pubmed: 37062240 DOI: doi:10.1016/j.bbrc.2023.04.002 ]
- 9h1 fab (Complex)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein complex with rmab 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 2 conformation
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8hec
Q-score: 0.358
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ Pubmed: 37062240 DOI: doi:10.1016/j.bbrc.2023.04.002 ]
- 9h1 fab (Complex)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein complex with rmab 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Local refinement of the SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8hed
Q-score: 0.469
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ Pubmed: 37062240 DOI: doi:10.1016/j.bbrc.2023.04.002 ]
- Sars-cov-2 wt spike glycoprotein rbd complex with 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- 9h1 fab (Complex)
- Sars-cov-2 spike glycoprotein rbd (Complex from Oryctolagus cuniculus)
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 8gzz
Q-score: 0.491
Guo H, Yang Y, Zhao T, Lu Y, Gao Y, Li T, Xiao H, Chu X, Zheng L, Li W, Cheng H, Huang H, Liu Y, Lou Y, Nguyen HC, Wu C, Chen Y, Yang H, Ji X
Commun Biol (2023) 6 pp. 364-364 [ DOI: doi:10.1038/s42003-023-04759-5 Pubmed: 37012333 ]
- Omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 1h1 fab (Complex)
- Sars-cov-2 omicron spike glycoprotein complex with 55a8 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rabbit monoclonal antibody 1h1 fab heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Rabbit monoclonal antibody 1h1 fab light chain (11 kDa, Protein from Oryctolagus cuniculus)
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8h00
Q-score: 0.484
Guo H, Yang Y, Zhao T, Lu Y, Gao Y, Li T, Xiao H, Chu X, Zheng L, Li W, Cheng H, Huang H, Liu Y, Lou Y, Nguyen HC, Wu C, Chen Y, Yang H, Ji X
Commun Biol (2023) 6 pp. 364-364 [ DOI: doi:10.1038/s42003-023-04759-5 Pubmed: 37012333 ]
- Omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 1h1 fab (Complex)
- Sars-cov-2 omicron spike glycoprotein complex with 55a8 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit monoclonal antibody 1h1 fab heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rabbit monoclonal antibody 1h1 fab light chain (11 kDa, Protein from Oryctolagus cuniculus)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8h01
Q-score: 0.342
Guo H, Yang Y, Zhao T, Lu Y, Gao Y, Li T, Xiao H, Chu X, Zheng L, Li W, Cheng H, Huang H, Liu Y, Lou Y, Nguyen HC, Wu C, Chen Y, Yang H, Ji X
Commun Biol (2023) 6 pp. 364-364 [ DOI: doi:10.1038/s42003-023-04759-5 Pubmed: 37012333 ]
- Omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 1h1 fab (Complex)
- Sars-cov-2 omicron spike glycoprotein complex with 55a8 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit monoclonal antibody 1h1 fab heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rabbit monoclonal antibody 1h1 fab light chain (11 kDa, Protein from Oryctolagus cuniculus)