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Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8vkk
Q-score: 0.439
Mannar D, Saville J, Poloni C, Zhu X, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S
To Be Published
Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with mouse ACE2 (conformation 2)
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 8vkl
Q-score: 0.331
Mannar D, Saville J, Poloni C, Zhu X, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S
To Be Published
- Sars-cov-2 xbb.1.5 spike protein trimer bound to 2 mouse ace2 molecules (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (71 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with mouse ACE2 (conformation 1)
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 8vkm
Q-score: 0.371
Mannar D, Saville J, Poloni C, Zhu X, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S
To Be Published
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (71 kDa, Protein from Mus musculus)
- Sars-cov-2 xbb.1.5 spike protein trimer bound to mouse ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8vkn
Q-score: 0.513
Mannar D, Saville J, Poloni C, Zhu X, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S
To Be Published
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Angiotensin-converting enzyme 2 (71 kDa, Protein from Mus musculus)
- Sars-cov-2 xbb.1.5 spike protein rbd bound to mouse ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2
Resolution: 2.68 Å
EM Method: Single-particle
Fitted PDBs: 8vko
Q-score: 0.26
Mannar D, Saville J, Poloni C, Zhu X, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S
To Be Published
- Processed angiotensin-converting enzyme 2 (70 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 xbb.1.5 spike protein trimer bound to 3 human ace2 molecules (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 8vkp
Q-score: 0.519
Mannar D, Saville J, Poloni C, Zhu X, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S
To Be Published
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Processed angiotensin-converting enzyme 2 (70 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 xbb.1.5 spike protein trimer bound to 3 human ace2 molecules (Complex from Severe acute respiratory syndrome coronavirus 2)
Mannar D, Saville J, Poloni C, Zhu X, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S
To Be Published
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with human ACE2
Resolution: 2.51 Å
EM Method: Single-particle
Fitted PDBs: 8dm5
Q-score: 0.312
Saville JW, Mannar D, Zhu X, Berezuk AM, Cholak S, Tuttle KS, Vahdatihassani F, Subramaniam S
Cell Rep (2023) 42 pp. 111964-111964 [ Pubmed: 36640338 DOI: doi:10.1016/j.celrep.2022.111964 ]
- Sars-cov-2 omicron ba.2 spike protein in complex with human ace2 (Complex)
- Human ace2 (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron ba.2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Processed angiotensin-converting enzyme 2 (70 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 8dm6
Q-score: 0.514
Saville JW, Mannar D, Zhu X, Berezuk AM, Cholak S, Tuttle KS, Vahdatihassani F, Subramaniam S
Cell Rep (2023) 42 pp. 111964-111964 [ Pubmed: 36640338 DOI: doi:10.1016/j.celrep.2022.111964 ]
- Sars-cov-2 omicron ba.2 spike protein in complex with human ace2 (Complex)
- Human ace2 (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron ba.2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Processed angiotensin-converting enzyme 2 (70 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with mouse ACE2
Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 8dm7
Q-score: 0.327
Saville JW, Mannar D, Zhu X, Berezuk AM, Cholak S, Tuttle KS, Vahdatihassani F, Subramaniam S
Cell Rep (2023) 42 pp. 111964-111964 [ Pubmed: 36640338 DOI: doi:10.1016/j.celrep.2022.111964 ]
- Mouse ace2 (Complex from Mus musculus)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron ba.2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 omicron ba.2 spike protein in complex with mouse ace2 (Complex)
- Angiotensin-converting enzyme 2 (71 kDa, Protein from Mus musculus)