EMD-82114

Single-particle
2.71 Å
EMD-82114
3D View Gallery
Deposition: 15/07/2026
Map released: 26/08/2026
Last modified: 26/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-82114

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-43sn summary report (pdf.gz) Map-43sn FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Alpha-7 nicotinic acetylcholine receptor bound to inhibitory bicyclic peptide KP1877 in a resting state

EMD-82114

Single-particle
2.71 Å
EMD-82114
3D View Gallery
Deposition: 15/07/2026
Map released: 26/08/2026
Last modified: 26/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Human nicotinic acetylcholine receptor alpha-7 bound to synthetic inhibitory peptide KP1877
Fitted models: 43sn

Deposition Authors: Chen H, Sun D, Tian C
Screening, synthesis and structural characterization of a novel bicyclic peptide inhibiting alpha 7 nicotinic acetylcholine receptor.
Yang X, Cui K, Cao X, Chen H, Tian C, Sun D
(2026) Chem Commun
PUBMED: 42574057
DOI: doi:10.1039/d6cc03853k
ISSN: 1364-548X