Electron Microscopy Data Bank

EMD-81945

Single-particle
2.98 Å

3D View Gallery

Deposition: 06/07/2026
Map released: 07/10/2026
Last modified: 07/10/2026

Overview 3D View Sample Experiment Validation Additional data Links

EMD-81945

LEN-bound HIV-1 capsid lattice within VLPs treated with PFO, C6 symmetry

EMD-81945

Single-particle
2.98 Å
EMD-81945

3D View Gallery

Deposition: 06/07/2026
Map released: 07/10/2026
Last modified: 07/10/2026

Overview 3D View Sample Experiment Validation Additional data Links

Sample Organism: Human immunodeficiency virus 1
Sample: HIV-1 capsid lattice
Fitted models: 43kn

Deposition Authors: Tanaka H, Machida S

Structural basis of lenacapavir-induced HIV-1 capsid defects during virion maturation.

Tanaka H, Morita R, Oka T, Fukushima M, Kita S , Sasaki M , Maenaka K, Machida S
(2026) Nat Commun , 17

PUBMED: 42773142
DOI: doi:10.1038/s41467-026-77803-7
ISSN: 2041-1723

Grant Support:

Japan Agency for Medical Research and Development (AMED): JP25fk0410078 (Japan)
Japan Agency for Medical Research and Development (AMED): JP25fk0310547 (Japan)
Japan Agency for Medical Research and Development (AMED): JP25fk0310530 (Japan)
Japan Agency for Medical Research and Development (AMED): JP25fk0310527 (Japan)
Japan Society for the Promotion of Science (JSPS): JP25K02504 (Japan)
Other government: 22T003 (Japan)
Other government: 23A1017 (Japan)
Other government: 25A1014 (Japan)
Japan Agency for Medical Research and Development (AMED): JP22ama121037 (Japan)
Japan Agency for Medical Research and Development (AMED): JP243fa627005 (Japan)
Japan Society for the Promotion of Science (JSPS): JP20H05873 (Japan)
Other government: 26A1005 (Japan)

EMD-81945

EMD-81945

Archive Files (Depositor)

Validation (wwPDB)

EMDB Annotations

EMDB Files

LEN-bound HIV-1 capsid lattice within VLPs treated with PFO, C6 symmetry

EMD-81945