EMD-80238
A complex of PTH1R/Gs bound to a PTHrP analogue with three beta-amino acids
EMD-80238
Single-particle2.86 Å
Deposition: 10/04/2026Map released: 03/06/2026
Last modified: 17/06/2026
Sample Organism:
Homo sapiens,
Lama glama,
synthetic construct
Sample: Complex of PTH1R/Gs bound to a modified PTHrP analogue
Fitted models: 25nx
Deposition Authors: Cary BP
,
Wootten D ,
Sexton PM ,
Gellman SH ,
Wook TK,
Shin J,
Gerrard EJ
Sample: Complex of PTH1R/Gs bound to a modified PTHrP analogue
Fitted models: 25nx
Deposition Authors: Cary BP
,
Wootten D ,
Sexton PM ,
Gellman SH ,
Wook TK,
Shin J,
Gerrard EJ
Altered Intracellular Trafficking as a Mechanism for Prolonged Duration of G Protein-Coupled Receptor Activation.
Kim TW ,
Gerrard EJ,
Shin J,
Gardella TJ,
Wootten D ,
Sexton PM ,
Cary BP ,
Gellman SH
(2026) J Am Chem Soc , 148 , 22045 - 22061
,
Gerrard EJ,
Shin J,
Gardella TJ,
Wootten D ,
Sexton PM ,
Cary BP ,
Gellman SH
(2026) J Am Chem Soc , 148 , 22045 - 22061
Grant Support:
- Australian Research Council (ARC): DE250101183 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 2025694 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 2026300 (Australia)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM151985 (United States)