EMD-77331

Single-particle
2.64 Å
EMD-77331
3D View Gallery
Deposition: 28/05/2026
Map released: 28/10/2026
Last modified: 28/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-77331

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-36ap summary report (pdf.gz) Map-36ap FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Mycobacterium tuberculosis DNA Gyrase catalytic core in complex with DNA and indole-3-acetyl-L-aspartic acid

EMD-77331

Single-particle
2.64 Å
EMD-77331
3D View Gallery
Deposition: 28/05/2026
Map released: 28/10/2026
Last modified: 28/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Mycobacterium tuberculosis
Sample: Tetrameric structure of APO InhA mutant I95P
Fitted models: 36ap

Deposition Authors: Rossini NO, Dias MVB, Coureux PD
Fragment-based drug discovery strategy reveals an unprecedented allosteric binding site in Mycobacterium tuberculosis DNA gyrase.
Shiroma ST, Rossini NO, Armenia JF, Silva CS, Souza PCT, Coureux PD, Osheroff N, Dias MVB
(2026) Eur.J.Med.Chem. , 320 , 119380 - 119380
PUBMED: 42822253
DOI: doi:10.1016/j.ejmech.2026.119380
ISSN: 0223-5234
ASTM: EJMCA5