EMD-76659

Single-particle
3.1 Å
EMD-76659
3D View Gallery
Deposition: 14/04/2026
Map released: 13/05/2026
Last modified: 08/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-76659
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 12pb summary report (pdf.gz) Map and 12pb FULL report (pdf.gz)
EMICSS annotations (xml)

Single particle cryo-EM structure of human MTCH2 (hyperactive mutant K25E Y235A V238D)

EMD-76659

Single-particle
3.1 Å
EMD-76659
3D View Gallery
Deposition: 14/04/2026
Map released: 13/05/2026
Last modified: 08/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: MTCH2 hyperactive mutant K25E Y235A V238D complexed with UCP1 nanobody
Fitted models: 12pb

Deposition Authors: Luo Z, Stevens TA, Voorhees RM
Structural evolution of the MTCH family of mitochondrial insertases.
Stevens TA, Luo Z, Lee C, Hazu M, Galatis EG, Inglis AJ, Guna A, Voorhees RM
(2026) Sci Adv , 12 , eaeh2957 - eaeh2957
PUBMED: 42308315
DOI: doi:10.1126/sciadv.aeh2957
ISSN: 2375-2548