EMD-76261

Single-particle
3.48 Å
EMD-76261
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Deposition: 23/03/2026
Map released: 10/06/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-76261
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 12ag summary report (pdf.gz) Map and 12ag FULL report (pdf.gz)
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Spermine-blocked open-state cryo-EM structure of human TRPV6 channel in cNW30 nanodiscs

EMD-76261

Single-particle
3.48 Å
EMD-76261
3D View Gallery
Deposition: 23/03/2026
Map released: 10/06/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: spermine-blocked open-state homotetrameric human TRPV6
Fitted models: 12ag

Deposition Authors: Neuberger A, Sobolevsky AI
Open-channel block of human TRPV6 by polyamine spermine.
Neuberger A, Veretenenko II, Shalygin A, Trofimov YA, Gudermann T, Chubanov V, Efremov RG, Sobolevsky AI
(2026) Nat Commun , 17
PUBMED: 42204171
DOI: doi:10.1038/s41467-026-73653-5
ISSN: 2041-1723