EMD-76088
GluA2-STZ pre-active state with partial agonist kainic acid (KA) at 25 degrees C (full-length composite)
EMD-76088
Single-particle3.98 Å
Deposition: 15/03/2026Map released: 23/09/2026
Last modified: 23/09/2026
Sample Organism:
Rattus norvegicus,
Mus musculus
Sample: GluA2-STZ pre-active state with partial agonist kainic acid (KA) at 25 degrees C (full-length composite)
Fitted models: 11vz
Deposition Authors: Newton TP
,
Yen LY,
Gangwar SP ,
Sobolevsky AI
Sample: GluA2-STZ pre-active state with partial agonist kainic acid (KA) at 25 degrees C (full-length composite)
Fitted models: 11vz
Deposition Authors: Newton TP
,
Yen LY,
Gangwar SP ,
Sobolevsky AI
Pre-activation and gating pathway of AMPA receptors revealed by full and partial agonists.
Newton TP ,
Aktolun M ,
Yelshanskaya MV ,
Alekseev AA,
Yen LY,
Gangwar SP ,
Sobolevsky IA,
Kurnikova MG ,
Sobolevsky AI
(2026) Nat Struct Mol Biol
,
Aktolun M ,
Yelshanskaya MV ,
Alekseev AA,
Yen LY,
Gangwar SP ,
Sobolevsky IA,
Kurnikova MG ,
Sobolevsky AI
(2026) Nat Struct Mol Biol
Grant Support:
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): F31NS147755 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS139087 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): F31NS132554 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS083660 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS107253 (United States)
- National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH/NIAMS): AR078814 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): CA206573 (United States)