EMD-75392

Single-particle
2.3 Å
EMD-75392
3D View Gallery
Deposition: 02/02/2026
Map released: 18/03/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75392
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 10qr summary report (pdf.gz) Map and 10qr FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of human VCP/p97 hexamer bound to ADP (DMSO control)

EMD-75392

Single-particle
2.3 Å
EMD-75392
3D View Gallery
Deposition: 02/02/2026
Map released: 18/03/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human VCP/p97 bound to ADP (DMSO control)
Fitted models: 10qr

Deposition Authors: Tamayo-Jaramillo D, Shen PS
Development and Structural Characterization of UTE-156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase.
Tamayo-Jaramillo D, Hegde S, Jia X, Coffman K, Vankayalapati H, Bearss D, Jones KB, Stark AW, Shen PS
(2026) Adv Sci , 13 , e20545 - e20545
PUBMED: 41793187
DOI: doi:10.1002/advs.202520545
ISSN: 2198-3844