EMD-75389

Single-particle
2.49 Å
EMD-75389
3D View Gallery
Deposition: 01/02/2026
Map released: 10/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75389

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-10qm summary report (pdf.gz) Map-10qm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

E.coli 50S ribosomal subunit bound to compound 48a

EMD-75389

Single-particle
2.49 Å
EMD-75389
3D View Gallery
Deposition: 01/02/2026
Map released: 10/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli
Sample: 50S ribosomal subunit
Fitted models: 10qm

Deposition Authors: Raskar T , Lee I
Structure-based design and synthesis of group A streptogramins that bind to the nascent peptide exit tunnel of the ribosome.
Lee IJ, Li Q, Raskar T , Pellegrino J , Ecker AK , Howard SY, Fraser JS, Seiple IB
(2026) Eur.J.Med.Chem. , 316 , 118947 - 118947
PUBMED: 42214237
DOI: doi:10.1016/j.ejmech.2026.118947
ISSN: 0223-5234
ASTM: EJMCA5