EMD-75279

Single-particle
2.9 Å
EMD-75279
3D View Gallery
Deposition: 27/01/2026
Map released: 29/04/2026
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75279

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-10ma summary report (pdf.gz) Map-10ma FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Closed Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with a closed active site (closed TL, SI3 and RH-FL)

EMD-75279

Single-particle
2.9 Å
EMD-75279
3D View Gallery
Deposition: 27/01/2026
Map released: 29/04/2026
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli
Sample: Eco RNAP his-elemental paused elongation complex
Fitted models: 10ma

Deposition Authors: Dhingra Y, Darst SA
RNA polymerase inhibitors reveal active-site motions essential for the nucleotide addition cycle.
Dhingra Y, Landick R, Campbell EA, Darst SA
(2026) PNAS , 123 , e2609228123 - e2609228123
PUBMED: 42378287
DOI: doi:10.1073/pnas.2609228123
ISSN: 1091-6490
ASTM: PNASA6