EMD-74656
Cryo-EM structure of SHIV-elicited CI93-1365 Fab in complex with HIV Env trimer Q23-SCT27
EMD-74656
Single-particle2.9 Å
Deposition: 21/12/2025Map released: 03/06/2026
Last modified: 22/07/2026
Sample Organism:
Macaca mulatta,
Human immunodeficiency virus
Sample: CI93-1365 Fab in complex with HIV envelope trimer
Fitted models: 9zrz
Deposition Authors: Roark RS, Shapiro LS, Kwong PD, Kwong PD
Sample: CI93-1365 Fab in complex with HIV envelope trimer
Fitted models: 9zrz
Deposition Authors: Roark RS, Shapiro LS, Kwong PD, Kwong PD
Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies.
Marchitto L,
Wagh K,
Roark RS,
Coleon S,
Li H,
Skelly AN,
Hogarty MP,
Habib R,
Ding W,
Ayyanathan K,
Liu W,
Sheng Z,
Guo Y,
Bal J,
Smith LM,
Sutherland LL,
Park Y,
Connell AJ,
Bibollet-Ruche F,
Lewis E,
Plante SJ,
Akeley MJ,
Lora J,
Zhao C,
Carey JW,
Martella CL,
Li Y,
Campion MS,
Lituchy MG,
Osbaldeston RA,
Gordon CG,
Albertus A,
Su J,
Noguchi C,
Tam YK,
Barbosa C,
Liang B,
Amereh K,
Li X,
Walsh AA,
Irvine DJ,
Andrabi R,
Edwards RJ,
Kreider EF,
Weissman D,
Shapiro L,
Kwong PD,
Korber BT,
Haynes BF,
Saunders KO,
Hahn BH,
Shaw GM
(2026) Nature
(2026) Nature
Grant Support:
