EMD-74399

Helical reconstruction
2.9 Å
EMD-74399
3D View Gallery
Deposition: 08/12/2025
Map released: 15/04/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74399
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9zld summary report (pdf.gz) Map and 9zld FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of hepatic amyloid fibril from a variant ATTRV122delta, single filament morphology

EMD-74399

Helical reconstruction
2.9 Å
EMD-74399
3D View Gallery
Deposition: 08/12/2025
Map released: 15/04/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: fibrils of ATTRV122delta
Fitted models: 9zld

Deposition Authors: Nguyen BA , Ahmed Y, Saelices L
Cryo-EM reveals structural variability of apolipoprotein A-I amyloid fibrils across organs, mutations, and clinical presentations.
Nguyen BA , Fernandez-Ramirez MDC , Bassett P , Singh V , Singh P , Pekala M, Villalon L, Ahmed Y, Lemoff A , Evers B, Lopez C, Kluve-Beckerman B, Saelices L
(2026) Nat Commun
PUBMED: 41991931
DOI: doi:10.1038/s41467-026-72150-z
ISSN: 2041-1723