EMD-73949

Single-particle
3.49 Å
EMD-73949
3D View Gallery
Deposition: 18/11/2025
Map released: 22/04/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73949

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9z9l summary report (pdf.gz) Map-9z9l FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Q23.MD39 in Complex with Fabs from antibodies CH01 and 35O22

EMD-73949

Single-particle
3.49 Å
EMD-73949
3D View Gallery
Deposition: 18/11/2025
Map released: 22/04/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Human immunodeficiency virus 1
Sample: Q23.MD39 Env trimer in Complex with CH01 and 35O22
Fitted models: 9z9l

Deposition Authors: Lin ZJ, Cui J, Du J, Habib R, Kulp D, Pallesen J
Deep mining of the human antibody repertoire identifies frequent and genetically diverse CDRH3 topologies targetable by vaccination.
Habib R, Solieva SO, Lin ZJ, Ghosh S, Bayruns K, Singh M, Agostino CJ, Tursi NJ, Sowers KJ, Huang J, Roark RS, Purwar M, Park Y, Ayyanathan K, Li H, Carey JW, Kim A, Park J, McCanna ME, Skelly AN, Chokkalingam N, Kriete S, Shupin N, Huynh A, Walker S, Sadeesh R, Laenger N, Du J, Cui J, Patel A, Escolano A, Kwong PD, Shapiro L, Bowman GR, Hahn BH, Shaw GM, Weiner DB, Pallesen J, Kulp DW
(2026) PNAS , 123 , e2532810123 - e2532810123
PUBMED: 42054357
DOI: doi:10.1073/pnas.2532810123
ISSN: 1091-6490
ASTM: PNASA6