EMD-73786

Single-particle
2.8 Å
EMD-73786
3D View Gallery
Deposition: 06/11/2025
Map released: 13/05/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73786
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9z3j summary report (pdf.gz) Map and 9z3j FULL report (pdf.gz)
EMICSS annotations (xml)

HCoV-NL63 S2' peptide bound to TMPRSS2 S441A (complexed with the H1H7 Fab and an anti-kappa-nanobody)

EMD-73786

Single-particle
2.8 Å
EMD-73786
3D View Gallery
Deposition: 06/11/2025
Map released: 13/05/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Human coronavirus NL63, Lama glama
Sample: HCoV-NL63 S2' peptide bound to TMPRSS2 S441A (complexed with the H1H7 Fab and an anti-kappa-nanobody)
Fitted models: 9z3j

Deposition Authors: McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D
TMPRSS2-mediated coronavirus spike activation and inhibition.
McCallum M, Case JB, Brown JT, Park YJ, Lee J, Sutherland E, Aggarwal A, Gibson C, Lempp FA, Stewart C, Tortorici MA, Sanapala S, Low JS, Asarnow D, Bohan D, Dellota Jr E, Merz B, Chawla B, Kar S, Lanzavecchia A, Sallusto F, Riley NM, Turville S, Purcell L, Diamond MS, Veesler D
(2026) Nat Struct Mol Biol
PUBMED: 42050172
DOI: doi:10.1038/s41594-026-01801-y
ISSN: 1545-9985
Grant Support: