EMD-73657

Single-particle
3.3 Å
EMD-73657
3D View Gallery
Deposition: 29/10/2025
Map released: 13/05/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73657
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9yyv summary report (pdf.gz) Map and 9yyv FULL report (pdf.gz)
EMICSS annotations (xml)

SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (S2 local refinement)

EMD-73657

Single-particle
3.3 Å
EMD-73657
3D View Gallery
Deposition: 29/10/2025
Map released: 13/05/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: VN01H1 Fab-bound SARS-CoV-2 E-FIC
Fitted models: 9yyv

Deposition Authors: Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D
TMPRSS2-mediated coronavirus spike activation and inhibition.
McCallum M, Case JB, Brown JT, Park YJ, Lee J, Sutherland E, Aggarwal A, Gibson C, Lempp FA, Stewart C, Tortorici MA, Sanapala S, Low JS, Asarnow D, Bohan D, Dellota Jr E, Merz B, Chawla B, Kar S, Lanzavecchia A, Sallusto F, Riley NM, Turville S, Purcell L, Diamond MS, Veesler D
(2026) Nat Struct Mol Biol
PUBMED: 42050172
DOI: doi:10.1038/s41594-026-01801-y
ISSN: 1545-9985