EMD-73458

Single-particle
2.5 Å
EMD-73458
3D View Gallery
Deposition: 20/10/2025
Map released: 17/12/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73458

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ytd summary report (pdf.gz) Map-9ytd FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Designed antibody vAB66 targeting PAP-HLA A*02:01

EMD-73458

Single-particle
2.5 Å
EMD-73458
3D View Gallery
Deposition: 20/10/2025
Map released: 17/12/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct, Lama glama
Sample: vAB-66 Fab bound to HLA-A*02:01 displaying PAP peptide with AD01 nanobofy fiducial
Fitted models: 9ytd

Deposition Authors: Jude KM , Garcia KC
Targeting peptide-MHC complexes with designed T cell receptors and antibodies.
Motmaen A , Jude KM , Wang N , Minervina A, Feldman D, Lichtenstein MA , Ebenezer A, Correnti C, Thomas PG, Garcia KC , Baker D, Bradley P
(2025) bioRxiv
PUBMED: 41332722
DOI: doi:10.1101/2025.11.19.689381
ISSN: 2692-8205