EMD-73373

Single-particle
4.13 Å
EMD-73373
3D View Gallery
Deposition: 16/10/2025
Map released: 10/06/2026
Last modified: 29/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73373

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9yrp summary report (pdf.gz) Map-9yrp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Full-length human VPS13C in complex with calmodulin from the CryoEM composite map

EMD-73373

Single-particle
4.13 Å
EMD-73373
3D View Gallery
Deposition: 16/10/2025
Map released: 10/06/2026
Last modified: 29/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Purified VPS13C bound to endogenous Calmodulin from Expi293F cells.
Fitted models: 9yrp

Deposition Authors: Li D, Reinisch KM
Cryo-EM structure of soluble VPS13C suggests its regulation by a conformational switch and by calmodulin.
Li D, Wang X, Hao H, Eden J, Hu B, Walsh EE, Parson MAH, Hamill S, Li Y, Chen G, Burke JE, De Camilli P, Reinisch KM
(2026) Mol Cell , 86 , 2843
PUBMED: 42413490
DOI: doi:10.1016/j.molcel.2026.06.028
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: