EMD-73221

Single-particle
3.32 Å
EMD-73221
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Deposition: 11/10/2025
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73221
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ynq summary report (pdf.gz) Map and 9ynq FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of Escherichia coli transcription initiation complex with GpA and des-hydroxy pseudouridimycin (des-hydroxy PUM)

EMD-73221

Single-particle
3.32 Å
EMD-73221
3D View Gallery
Deposition: 11/10/2025
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli str. K-12 substr. MG1655
Sample: Escherichia coli transcription initiation complex with GpA and des-hydroxy pseudouridimycin (des-hydroxy PUM)
Fitted models: 9ynq

Deposition Authors: You LL, Ebright RH
Solid-phase synthesis and biological evaluation of des-hydroxy pseudouridimycin analogs.
Anwar AF, You L, Degen D, Burns KJ, Garza MJ, Ebright RH, Del Valle JR
(2026) Acs Med.Chem.Lett.
PUBMED: 41890570
DOI: doi:10.1021/acsmedchemlett.5c00684
ISSN: 1948-5875