EMD-72972
AM12-340 Fab in complex with HIV-1 Env 5MUT-3fill SOSIP
EMD-72972
Single-particle4.3 Å
Deposition: 30/09/2025Map released: 10/06/2026
Last modified: 08/07/2026
Sample Organism:
Human immunodeficiency virus 1,
Macaca mulatta
Sample: HIV-1 Envelope protein
Fitted models: 9yhs
Deposition Authors: Gristick HB
,
Gavor E ,
Bjorkman PJ
Sample: HIV-1 Envelope protein
Fitted models: 9yhs
Deposition Authors: Gristick HB
,
Gavor E ,
Bjorkman PJ
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design.
Skelly AN,
Gristick HB ,
Li H,
Gavor E ,
Connell AJ,
Kreider EF,
Marchitto L,
Hogarty MP,
Newby ML,
Allen JD,
Liu W,
West Jr AP,
Ayyanathan K,
Campion MS,
Winters K,
Gordon CG,
Osbaldeston RA,
Akeley MJ,
Lewis E,
Li Y,
Singh A,
Cruickshank K,
Park Y,
Zhao C,
Li X,
Amereh K,
Van Itallie E,
Carey JW,
Albertus A,
DeLaitsch AT,
Keeffe JR,
Lituchy MG,
Walsh AA,
Morris DJ,
Habib R,
Bibollet-Ruche F,
Mishra N,
Avillion G,
Koranda NS,
Plante SJ,
Martella CL,
Lora J,
Wang EJD,
Lewis MG,
Martin MA,
Nussenzweig MC,
Seaman MS,
Irvine DJ,
Wiehe KJ,
Haynes BF,
Wagh K,
Korber B,
Andrabi R,
Crispin M,
Weissman D,
Bjorkman PJ ,
Hahn BH,
Shaw GM
(2026) Science , 392 , eaec6396 - eaec6396
,
Li H,
Gavor E ,
Connell AJ,
Kreider EF,
Marchitto L,
Hogarty MP,
Newby ML,
Allen JD,
Liu W,
West Jr AP,
Ayyanathan K,
Campion MS,
Winters K,
Gordon CG,
Osbaldeston RA,
Akeley MJ,
Lewis E,
Li Y,
Singh A,
Cruickshank K,
Park Y,
Zhao C,
Li X,
Amereh K,
Van Itallie E,
Carey JW,
Albertus A,
DeLaitsch AT,
Keeffe JR,
Lituchy MG,
Walsh AA,
Morris DJ,
Habib R,
Bibollet-Ruche F,
Mishra N,
Avillion G,
Koranda NS,
Plante SJ,
Martella CL,
Lora J,
Wang EJD,
Lewis MG,
Martin MA,
Nussenzweig MC,
Seaman MS,
Irvine DJ,
Wiehe KJ,
Haynes BF,
Wagh K,
Korber B,
Andrabi R,
Crispin M,
Weissman D,
Bjorkman PJ ,
Hahn BH,
Shaw GM
(2026) Science , 392 , eaec6396 - eaec6396
Grant Support: