EMD-72723

Helical reconstruction
3.29 Å
EMD-72723
3D View Gallery
Deposition: 15/09/2025
Map released: 22/04/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72723

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ya7 summary report (pdf.gz) Map-9ya7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

KIF1A R350G bound to microtubules in the apo state

EMD-72723

Helical reconstruction
3.29 Å
EMD-72723
3D View Gallery
Deposition: 15/09/2025
Map released: 22/04/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Sus scrofa, Homo sapiens
Sample: KIF1A R350G bound to microtubules in the apo state
Fitted models: 9ya7

Deposition Authors: Shatarupa A, Rao L, Asenjo AB, Gennerich A, Sosa H
Pathogenic KIF1A R350 mutations disrupt a conserved and conformation-dependent kinesin-tubulin salt bridge.
Shatarupa A, Rao L, Asenjo AB, Gennerich A, Sosa H
(2026) Nat Commun , 17
PUBMED: 41912506
DOI: doi:10.1038/s41467-026-71026-6
ISSN: 2041-1723