EMD-72384

Single-particle
2.55 Å
EMD-72384
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Deposition: 28/08/2025
Map released: 29/04/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72384
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9y04 summary report (pdf.gz) Map and 9y04 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human VCP/p97-R89W mutant bound to ATPgammaS

EMD-72384

Single-particle
2.55 Å
EMD-72384
3D View Gallery
Deposition: 28/08/2025
Map released: 29/04/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: VCP/p97 R89W mutant bound to ATPgammaS
Fitted models: 9y04

Deposition Authors: Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS
Mutations in VCP cause Adams-Oliver syndrome with or without pulmonary hypertension.
Lehman A, Ahmed S, Mohajeri A, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Aparecida Magno J, Hannibal M, Kovacevic G, Kuburovic V, Suzanne Lewis ME, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS
(2026) Genet Med , 102579 - 102579
PUBMED: 41979051
DOI: doi:10.1016/j.gim.2026.102579
ISSN: 1530-0366