EMD-72277

Single-particle
2.86 Å
EMD-72277
3D View Gallery
Deposition: 22/08/2025
Map released: 29/07/2026
Last modified: 29/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72277

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9q6f summary report (pdf.gz) Map-9q6f FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM map of Plasmodium falciparum 20S proteasome bound to an asparagine-ethylenediamine based inhibitor TDI6245

EMD-72277

Single-particle
2.86 Å
EMD-72277
3D View Gallery
Deposition: 22/08/2025
Map released: 29/07/2026
Last modified: 29/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Plasmodium falciparum
Sample: Complex of Plasmodium falciparum 20S with inhibitor TDI-6245
Fitted models: 9q6f

Deposition Authors: Hsu HC, Li H

Structure-activity relationship study of antimalarial asparagine derived proteasome inhibitors
Zhang H, Hsu HC, Zhan W, Hara R, Visone J, Imaeda T, Okamoto R, Fajtova P, Sato K, Michino M, Garg S, Kreutzfeld O, Tumwebaze P, Orena S, Okitwi M, Aso K, Cooper R, Rosenthal PJ, Meinke PT, Foley M, ODonoghue AJ, Li H, Kirkman LA, Lin G
To Be Published