EMD-72151
Structure of the Measles virus Fusion glycoprotein ectodomain in complex with two neutralizing antibodies 4F09 and 3A12
EMD-72151
Single-particle2.3 Å
Deposition: 14/08/2025Map released: 01/07/2026
Last modified: 01/07/2026
Sample Organism:
Homo sapiens,
Measles morbillivirus
Sample: Structure of the Measles virus Fusion glycoprotein ectodomain in complex with two neutralizing antibodies 4F09 and 3A12
Fitted models: 9q26
Deposition Authors: Zyla D
,
Acciani M,
Niemeyer G,
Saphire EO
Sample: Structure of the Measles virus Fusion glycoprotein ectodomain in complex with two neutralizing antibodies 4F09 and 3A12
Fitted models: 9q26
Deposition Authors: Zyla D
,
Acciani M,
Niemeyer G,
Saphire EO
Human neutralizing antibodies targeting the measles virus hemagglutinin and fusion surface proteins.
Acciani M,
Zyla D ,
Niemeyer G,
Harkins S,
Parekh D,
Pawlack E,
Lacarbonara D,
Kansara D ,
Ackerman ME,
Niewiesk S,
Porotto M,
Hastie KM,
Saphire EO
(2026) Cell Host Microbe , 34 , 1067 - 1081.e12
,
Niemeyer G,
Harkins S,
Parekh D,
Pawlack E,
Lacarbonara D,
Kansara D ,
Ackerman ME,
Niewiesk S,
Porotto M,
Hastie KM,
Saphire EO
(2026) Cell Host Microbe , 34 , 1067 - 1081.e12
Grant Support:
- Swiss National Science Foundation: P2EZP3_195680 (Switzerland)
- Swiss National Science Foundation: P500PB_210992 (Switzerland)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS105699 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS091263 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI176833 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): 1R56AI183536-01A1 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): 5R21AI180456-02 (United States)