EMD-72007

Composite map
Single-particle
3.2 Å
EMD-72007 Deposition: 06/08/2025
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72007

Unlatched-state loperamide-mu opioid receptor-Gi GDPbS complex (rebound)

EMD-72007

Composite map
Single-particle
3.2 Å
EMD-72007 Deposition: 06/08/2025
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Loperamide-mu opioid receptor in complex with Gai-GDPbS, Gb1 and Gg2
Fitted models: 9py3

Deposition Authors: Gati C, Han GW, Khan S

Ligand efficacy is driven by conformational control of nucleotide exchange at the mu opioid receptor.

Khan S, Han GW, Gati C
To Be Published