EMD-71898

Helical reconstruction
2.73 Å
EMD-71898
3D View Gallery
Deposition: 04/08/2025
Map released: 18/03/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71898

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9pw3 summary report (pdf.gz) Map-9pw3 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of renal amyloid fibril from a variant apolipoprotein A-I R173P amyloidosis patient

EMD-71898

Helical reconstruction
2.73 Å
EMD-71898
3D View Gallery
Deposition: 04/08/2025
Map released: 18/03/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: amyloid fibrils of apoliprotein A-I amyloidosis, variant R173P from renal tissue
Fitted models: 9pw3

Deposition Authors: Nguyen BA , Saelices L
Cryo-EM reveals structural variability of apolipoprotein A-I amyloid fibrils across organs, mutations, and clinical presentations.
Nguyen BA , Fernandez-Ramirez MDC, Bassett P, Singh V, Singh P, Pekala M, Villalon L, Ahmed Y, Lemoff A, Evers B, Lopez C, Kluve-Beckerman B, Saelices L
(2026) Nat Commun , 17
PUBMED: 41991931
DOI: doi:10.1038/s41467-026-72150-z
ISSN: 2041-1723