EMD-71303

Single-particle
2.74 Å
EMD-71303
3D View Gallery
Deposition: 18/06/2025
Map released: 23/07/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71303

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9p6b summary report (pdf.gz) Map-9p6b FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of full-length human TRPV1 in the presence of alpha-humulene

EMD-71303

Single-particle
2.74 Å
EMD-71303
3D View Gallery
Deposition: 18/06/2025
Map released: 23/07/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: full-length human TRPV1 in the presence of alpha-humulene
Fitted models: 9p6b

Deposition Authors: Talyzina IA, Sobolevsky AI
Structural basis of the inhibition of TRPV1 by analgesic sesquiterpenes.
Sanchez-Hernandez R , Benitez-Angeles M , Talyzina IA, Llorente I , Gonzalez-Avendano M, Sierra F, Mendez-Resendiz A, Mercado F , Vergara-Jaque A, Sobolevsky AI , Islas LD , Rosenbaum T
(2025) PNAS , 122 , e2506560122 - e2506560122
PUBMED: 40663614
DOI: doi:10.1073/pnas.2506560122
ISSN: 1091-6490
ASTM: PNASA6